Clinical trials
Single-ventricle clinical trials
Below are recruiting single-ventricle clinical trials, each written for real people, not researchers. We’re tracking 10 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05262907Recruiting
Study of heart imaging in people with one pumping ventricle
This study uses routine heart scans (either echocardiogram or MRI) to better understand single-ventricle heart conditions. It may help improve how doctors evaluate and monitor your heart over time.
Durham, North CarolinaAges Any age - NCT07087782Recruiting
Early high-calorie formula for infants with single ventricle heart condition
This trial tests whether starting a special high-calorie formula (Fortini) early helps infants with a single ventricle heart condition grow better and have fewer health problems between surgeries. It might improve outcomes before their next surgery.
Corpus Christi, TexasAges birth–6 months - NCT04467671RecruitingPhase 2
Tested new blood vessel graft for a heart surgery
This trial studies whether a newer “tissue-engineered” blood vessel graft is safe and works well in children who need a specific heart surgery connection outside the heart. It may help by offering a new type of graft, but your team will screen for size and medical factors first.
Columbus, OhioAges Any age - NCT07220226Recruiting
Fontan circulation and venous compression study
This trial looks at how blood flow works in people with Fontan circulation, who have a unique heart surgery. It aims to understand vein compression and may help guide future care.
Dallas, TexasAges 18–45 - NCT04106479Recruiting
Baby heart ultrasound study in newborn congenital heart defects
This study records newborn heart measurements (using medical imaging) to compare babies with certain congenital heart defects to healthy-term babies. The goal is to see how well one test matches another, which may help doctors better understand heart conditions in newborns.
Montreal, QuebecAges birth–1 week - NCT06150950Recruiting
Exercise rehab for Fontan failure
This trial tests if a supervised exercise program (cardiac rehabilitation) can help people who have had a Fontan procedure and are now experiencing heart failure symptoms. It aims to improve your strength, stamina, and overall well-being.
Stanford, CaliforniaAges 18 years+ - NCT06434207Recruiting
Heart defect study in newborns to understand blood clots
This study looks at tiny particles from cells in newborns with heart defects to understand blood clot risks. It aims to find ways to prevent clots after heart surgery.
Boston, MassachusettsAges 1 day–1 week - NCT06538571Recruiting
Infant heart study using light to check oxygen levels
This study uses a light-based sensor placed on the skin to measure oxygen levels in infants with a single heart ventricle before their Glenn surgery. The goal is to see if these measurements can help predict how well they do between surgeries.
Oak Lawn, IllinoisAges Up to 6 months - NCT06918795Recruiting
Fontan Fitness Trial: Home exercise for better heart health
This study tests whether a home-based exercise training program can improve fitness in people with Fontan circulation. Participants will do regular aerobic exercise and be monitored for changes in heart and lung function over time.
Philadelphia, PennsylvaniaAges 10–17 - NCT07073612Recruiting
Fontan stent study for liver stiffness and exercise
This study looks at whether placing a stent in the Fontan blood vessel can improve liver health and exercise ability in teenagers and young adults. If you are between 12 and 21 years old and need a stent in your Fontan pathway, you may be able to join.
Los Angeles, CaliforniaAges 12–21
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Common questions
- Are there clinical trials for single-ventricle?
- Yes. Clin2 currently lists 10 recruiting single-ventricle studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a single-ventricle trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a single-ventricle trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.