Clinical trials
Soft Tissue clinical trials
Below are recruiting soft tissue clinical trials, each written for real people, not researchers. We’re tracking 322 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07782125Recruiting
Gum graft alternatives for dental implants
This study compares two ways to add gum tissue around a dental implant to improve its appearance and health. One method uses a small piece of your own gum tissue, and the other uses a special collagen material.
Ankara, Yeni̇mahalleAges 18–65 - NCT06841419Recruiting
Rebuilding soft tissue with a thigh flap
This trial uses a flap of skin and muscle from your thigh to cover wounds on the hip, thigh, or lower belly that can't be stitched closed. It may help if you have a clean wound needing reconstruction.
SohagAges Any age - NCT04751409RecruitingPhase 2
Less versus more follow-up after sarcoma surgery
This trial compares two schedules of post-treatment check-ups to see which one better supports patient quality of life. You’d fill out surveys for up to two years to measure how you feel over time.
Houston, TexasAges 18 years+ - NCT07649239Recruiting
Gum Grafting Methods for Dental Implants in Front Teeth
This trial compares two techniques to improve the appearance and health of gum tissue around dental implants in your front teeth. One uses a special blood product (PRF), and the other uses a traditional gum graft. The goal is to see which gives better-looking results.
Ajman, Ajman EmirateAges 20–70 - NCT07385313RecruitingPhase 4
Sheep Tissue and Vacuum Therapy for Deep Wound Healing
This trial tests a combination of a special sheep-derived material (OFM) and a vacuum dressing to help rebuild deep wounds with exposed bone or tendon. It aims to speed up healing in arm or leg injuries.
Aurora, ColoradoAges 18 years+ - NCT04766255RecruitingPhase 4
Comparing materials to thicken gum tissue around dental implants
This study compares three types of graft (tissue/covering materials) to help build up thicker gum and soft tissue around a dental implant. It may help improve appearance and protect the implant area when you have thin or missing gum tissue.
Sant Cugat del Vallès, BarcelonaAges 18 years+ - NCT07056959Recruiting
Collagen matrix for gum health around implants
This trial tests whether a collagen matrix can help improve the gum tissue around dental implants that have thin or insufficient gum width. It may help patients with narrow gum bands around their implants.
DubaiAges 21 years+ - NCT07436091Enrolling by invitation
Using pig skin to improve gum thickness around dental implants
This study tests a material made from pig skin (porcine dermis) to see if it can help make the gum tissue thicker and healthier around dental implants. It may be a good option for people who already have an implant in a back tooth area and need more gum tissue.
PortoAges 18 years+ - NCT07507773RecruitingPhase 2
Radiation before surgery for limb or trunk wall sarcoma
This trial tests a shorter course of radiation given before surgery for soft tissue sarcoma in the arms, legs, or trunk wall. It aims to see if this approach works well long-term and may help you keep your limb.
LilleAges 18 years+ - NCT03818412Recruiting
Liquid biopsy for soft tissue sarcoma
This study checks if a blood test can detect DNA from soft tissue sarcomas. The goal is to see if circulating tumor DNA can help doctors monitor the disease and plan treatment.
Toronto, OntarioAges 18 years+ - NCT04577014RecruitingPhase 1/Phase 2
Retifanlimab plus chemotherapy for advanced soft tissue sarcoma
This trial tests retifanlimab (an immunotherapy that helps your immune system recognize cancer) combined with gemcitabine and docetaxel chemotherapy. It’s for people with advanced soft tissue sarcoma that can’t be safely removed with surgery, aiming to shrink tumors and improve outcomes.
New York, New YorkAges 18 years+ - NCT04757337RecruitingPhase 3
Oral chemotherapy comparison for older advanced soft-tissue cancer
This trial compares two chemotherapy medicines—oral cyclophosphamide versus doxorubicin—in people age 65 and older with advanced soft-tissue sarcoma that can’t be cured with surgery or radiation. It aims to see which treatment works better and is more tolerable for this age group.
ToulouseAges 65 years+ - NCT05526417Recruiting
Prehab program before treatment for deep leg soft tissue cancer
This trial tests an individualized “prehab” program (exercises and preparation before treatment) to improve recovery and surgical outcomes for adults with deep soft tissue sarcoma in the leg. It’s meant to help your body be as ready as possible for radiotherapy and surgery.
Scottsdale, ArizonaAges 18 years+ - NCT06180642Recruiting
Ultrasound for arm tissue after breast cancer
This study uses ultrasound to examine arm tissue in women who have had breast cancer. It aims to see if ultrasound can reliably detect changes in arm soft tissue, which may help identify or prevent arm swelling and stiffness after treatment.
AntwerpAges 18 years+ - NCT06385288Recruiting
Blood and tissue study in high-risk sarcoma
This study collects blood and tissue samples from people with high-risk soft tissue sarcoma before their surgery. The goal is to learn how the immune system responds to pre-surgery treatments like radiation and hyperthermia (heat therapy).
Tübingen, Baden-WurttembergAges 18 years+ - NCT06498648RecruitingPhase 1/Phase 2
Abemaciclib with gemcitabine for soft tissue sarcoma
This trial tests whether adding the targeted drug abemaciclib to standard chemotherapy (gemcitabine) works better against certain soft tissue sarcomas. It is for people whose tumors have a normal Rb gene, which may help the drug work.
Houston, TexasAges 18 years+ - NCT06797999RecruitingPhase 1/Phase 2
Study of ADCE-D01 for soft tissue sarcoma
This trial tests a new drug called ADCE-D01 for people with soft tissue sarcoma that has spread or cannot be removed by surgery. The goal is to see if it is safe and effective.
Aurora, ColoradoAges 18 years+ - NCT06837688Recruiting
Comparing two methods to improve gum around a single front tooth implant
This study compares two methods to improve gum tissue around a single dental implant in the front upper jaw. It may help you if you have a missing front tooth, healthy gums, and enough bone and gum width for an implant.
DamascusAges 18–60 - NCT06968780Recruiting
Comparing two gum grafts for dental implants in the upper jaw
This trial compares two surgical techniques using tissue from the cheek or the roof of the mouth to improve gum health around special implants placed in the cheekbone. It may be an option if you have severe bone loss in your upper jaw and need implants but don't have enough bone for standard ones.
Cairo, Giza GovernorateAges 18 years+ - NCT07062003Recruiting
Minibeam radiation for skin or soft tissue tumors
This trial tests a new type of radiation called minibeam therapy for people with skin or soft tissue cancers that have come back or spread. It's designed to help shrink tumors that standard treatments haven't worked well for, and it uses a special device to focus the radiation more precisely.
Rochester, MinnesotaAges 18 years+ - NCT07071727Recruiting
Short course of radiation before surgery for soft tissue sarcoma
This trial tests whether a shorter course of radiation before surgery is effective for soft tissue sarcomas in certain locations. It aims to make treatment more convenient while maintaining good results.
AmsterdamAges 18 years+ - NCT07169344RecruitingPhase 2
Short course radiation before sarcoma surgery
This trial tests a shorter, 3-week course of radiation therapy (using protons or standard X-rays) given before surgery for localized soft tissue sarcoma. It aims to see if this approach is safe and effective for treating the tumor while reducing side effects.
BergenAges 18 years+ - NCT07173972RecruitingPhase 2
Proton radiation for inoperable soft tissue sarcoma
This trial studies a high-dose, shortened course of proton beam radiation for people with soft tissue sarcoma that cannot be removed by surgery. It aims to improve tumor control while reducing side effects.
BergenAges 18 years+ - NCT03138161RecruitingPhase 1/Phase 2
Testing three medicines for previously treated soft-tissue sarcoma
This trial tests trabectedin plus ipilimumab and nivolumab in people with advanced soft-tissue sarcoma that has already been treated. It aims to see how well this combination works and how safely it can be given.
Santa Monica, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for soft tissue?
- Yes. Clin2 currently lists 322 recruiting soft tissue studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a soft tissue trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a soft tissue trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.