Clinical trials
Stress and Anxiety clinical trials
Below are recruiting stress and anxiety clinical trials, each written for real people, not researchers. We’re tracking 167 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06706323Recruiting
Depression after heart surgery study
This study looks at depressive symptoms in people who have had heart bypass surgery. It aims to understand how patients feel emotionally after surgery and may help improve care.
ZurichAges 18–90 - NCT07219056Recruiting
Sound therapy for adults with trauma and addiction
This trial tests a sound-based program (Safe & Sound Protocol) to help adults with both trauma and substance use disorder in residential treatment. It aims to see if this gentle listening therapy can calm the nervous system and support recovery.
Wernersville, PennsylvaniaAges 18–75 - NCT07147634Recruiting
Outdoor science classes and child well-being study
This study tests whether outdoor science lessons improve well-being, learning, and connection to nature in 5th and 6th graders. It also looks at how outdoor time might help with eco-anxiety and stress.
Montreal, QuebecAges Any age - NCT07088939Recruiting
Online skills course for depression and anxiety
This trial tests an online course that teaches skills to manage emotions. It is for people in Ontario with mild depression or anxiety who are not currently in therapy.
Windsor, OntarioAges 18 years+ - NCT06899165RecruitingPhase 2
Psilocybin therapy for inherited trauma
This trial tests whether psilocybin (a psychedelic substance) combined with therapy can help adult children of genocide survivors who experience symptoms of trauma, depression, or anxiety. The goal is to see if this approach can reduce the emotional impact of intergenerational trauma.
New York, New YorkAges 18 years+ - NCT06839859RecruitingPhase 2
Family Acceptance Project online pilot study
This trial tests an online program called Family Acceptance Project to help LGBTQ+ youth of color and their families improve acceptance and reduce rejection. You and a caregiver will join separate online group sessions to learn communication and support skills.
Ann Arbor, MichiganAges 14 years+ - NCT06652503Recruiting
Student wellness and emotional growth program
This trial tests a program called SWAG-R designed to help NSU undergraduate students build resilience and manage emotions. It may be a good fit if you are not currently in therapy or dealing with serious mental health issues.
Fort Lauderdale, FloridaAges 18 years+ - NCT06603064Recruiting
Brain stimulation study on stress and emotions
This study uses brain scans to understand how your brain responds to stress. You will complete tasks and answer questions while undergoing an MRI to help researchers learn more about emotional responses.
Pittsburgh, PennsylvaniaAges 30–50 - NCT05712057Recruiting
Brain stimulation vs therapy for emotion regulation problems
This trial compares a type of brain stimulation (rTMS) to therapy to help people better manage strong emotions. You may be eligible if you have ongoing difficulties with emotion control and meet specific mood, anxiety, or related symptom criteria.
Durham, North CarolinaAges 18–55 - NCT05040711Recruiting
Mindfulness app for serious illness patients and caregivers
This study tests whether a mindfulness training delivered through a phone or tablet can help people and their caregivers cope with serious illness. You may be eligible if you’re 60 or older (as a patient) or an adult caregiver, and if simple screening questionnaires suggest you could benefit.
Livingston, New JerseyAges 21 years+ - NCT04335487Recruiting
Online therapy program for PTSD symptoms in public safety workers
This study tests an internet-based cognitive-behavioral therapy (an online talk-therapy style program that helps you manage thoughts and feelings) to reduce PTSD symptoms in public safety personnel. You may be able to join if you have PTSD-like symptoms and can safely take part in online treatment.
Regina, SaskatchewanAges 18 years+ - NCT07717385Recruiting
90-day trial of a probiotic for stress and sleep
This study tests whether a daily probiotic capsule called Neuralli Mood can help adults who feel stressed, have trouble sleeping, or experience low mood. It lasts 90 days and involves taking two capsules each day and filling out online surveys.
New York, New YorkAges 18 years+ - NCT06811311Recruiting
Hypnotherapy and Brain Activity in Generalized Anxiety Disorder
This study uses EEG (a brain wave test) to see how Ericksonian hypnotherapy, a gentle type of hypnosis, affects brain activity and anxiety symptoms in people with Generalized Anxiety Disorder (GAD) who are not currently in treatment or taking medication for anxiety.
IstanbulAges 18–65 - NCT05074901Recruiting
Using a health app in France with virtual support
This trial tests whether a digital health app (with “virtual agents,” like guided prompts/support) can improve people’s health outcomes. You may help the study by using the app and completing its questionnaires.
BordeauxAges 18 years+ - NCT07792837Recruiting
Online intuitive eating program for pregnant women with obesity
This study tests an online program that helps pregnant women with obesity learn to eat intuitively, which means listening to their body's hunger and fullness signals instead of dieting. The goal is to support their well-being during pregnancy.
San Diego, CaliforniaAges 18 years+ - NCT07656623Recruiting
Probiotics for IBS with stomach issues and stress
This trial tests whether a special probiotic blend can help people with irritable bowel syndrome (IBS) who also have stomach symptoms like heartburn, bloating, or nausea, and feel anxious, depressed, or stressed. It aims to see if the probiotic improves both gut and mood symptoms.
Hanoi, HanoiAges 18 years+ - NCT04276922Recruiting
Creative arts program to reduce healthcare burnout
This study tests a creative arts program to help reduce burnout symptoms in people who work in hospitals. If you’re feeling emotionally drained or disconnected at work, participating may help you build coping and well-being skills.
Aurora, ColoradoAges 18–85 - NCT06773338Recruiting
Can playing Tetris improve mental health for migrants?
This study tests if playing the game Tetris can help reduce stress and improve mood for Arabic-speaking immigrants who have applied for asylum. You would play Tetris a few times and report how you feel.
The Hague, NLAges 18 years+ - NCT07292610Recruiting
Nut study for young university students
This trial tests whether eating nuts regularly can improve mental health in young adults. If you are a university student aged 18-25, you may be able to join.
Cuenca, CuencaAges 18–24 - NCT06455397Recruiting
Building emotional awareness and mental health for parents
This trial tests a program called BEAM that helps parents and caregivers of young children (ages 2–5) manage stress, depression, anxiety, or anger. You'll get support from a peer coach through check-ins and learn skills to feel better.
Winnipeg, ManitobaAges 18 years+ - NCT06722287Recruiting
Phone support for family caregivers in Thailand
This study tests a mobile program to support the mental health of family caregivers in Thailand. You participate from home using your phone.
BangkokAges 18–80 - NCT06635486Recruiting
Mental health support for Venezuelans in Lima
This study offers mental health support to Venezuelan adults living in Lima who are feeling anxious, depressed, or have experienced trauma. It will check if you have signs of depression, anxiety, or post-traumatic stress and provide help if you do.
LimaAges 18 years+ - NCT06654414Recruiting
Smoking cessation support for transgender and gender-diverse adults
This study tests a skills-based program to help transgender and gender-diverse adults quit smoking or vaping. The program focuses on managing stress related to identity and health, and may be more supportive than standard quit programs.
Boston, MassachusettsAges 18 years+ - NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+
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Common questions
- Are there clinical trials for stress and anxiety?
- Yes. Clin2 currently lists 167 recruiting stress and anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stress and anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stress and anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.