Clinical trials
Substance Use Risk clinical trials
Below are recruiting substance use risk clinical trials, each written for real people, not researchers. We’re tracking 55 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04929288Recruiting
Study how hormones affect alcohol risk in men and women
This study looks at how brain activity and hormone-related factors may help explain differences in alcohol risk between men and women. It may help researchers understand why alcohol use differs by sex and how risk develops.
Columbus, OhioAges 21–26 - NCT06105853Recruiting
Stress and brain activity in alcohol use disorder
This study looks at how people with alcohol use disorder respond to stress and what happens in the brain. You'll use a smartphone and may have an MRI scan to understand your stress responses.
Mannheim, Baden-WurttembergAges 18–65 - NCT04485871Recruiting
Omega-3 supplements to lower diabetes risk in at-risk adults
This trial tests whether taking omega-3 fatty acids can reduce risk factors for developing diabetes in people with normal cholesterol but other risk factors. You might be asked to follow study visits and dietary/health restrictions for about 33 weeks.
Montreal, QuebecAges 45–74 - NCT05142267Recruiting
Study stress and opioid-risk factors in chronic low back pain
This study looks at how stress and the body’s natural opioid/cannabinoid systems may relate to risk of opioid misuse. It tests people with long-lasting low back pain to see what biological or psychological factors might increase or lower that risk.
Nashville, TennesseeAges 18 years+ - NCT06548490RecruitingPhase 2
Semaglutide for Opioid Use Disorder
This study tests whether a once-weekly injection of semaglutide (a GLP-1 receptor agonist) can reduce opioid use in people who are already on buprenorphine or methadone but still using opioids. It lasts about 19 weeks.
Baltimore, MarylandAges 18–75 - NCT07665502Enrolling by invitation
Smartphone app to boost opioid treatment for women facing violence
This study tests a smartphone app (WINGS+++) to help women who have experienced intimate partner violence and trauma improve their engagement with medication for opioid use disorder (MOUD). The goal is to see if the app makes it easier to start and stay on treatment.
New York, New YorkAges 18 years+ - NCT05519475RecruitingPhase 2
Gene-silencing medicine trial for adults with MASH and liver scarring
This Phase 2 study tests a gene-silencing treatment to improve chronic liver disease called MASH, especially in people with certain genetic risk. You may be eligible if you have MASH with moderate-to-advanced scarring and specific test results, and if other liver causes and recent substance/alcohol issues don’t apply.
Chandler, ArizonaAges 18–75
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Common questions
- Are there clinical trials for substance use risk?
- Yes. Clin2 currently lists 55 recruiting substance use risk studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a substance use risk trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a substance use risk trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.