Clinical trials
Tooth Loss clinical trials
Below are recruiting tooth loss clinical trials, each written for real people, not researchers. We’re tracking 35 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04281056Recruiting
Tooth loss and dentures: taste and food preferences
This study looks at how losing teeth and wearing dentures affects your mouth sensations and your food choices. It compares people who are fully without teeth (and use dentures) with people who still have their natural teeth.
ParisAges 18–79 - NCT07393997Recruiting
Tooth transplant with platelet-rich fibrin for young patients
This trial tests a tooth transplant method that uses a healthy tooth from elsewhere in your mouth to replace a missing tooth. A special protein-rich material (platelet-rich fibrin) is placed around the new tooth to help it heal and grow roots. It's designed for children, teens, and young adults who cannot get dental implants.
BariAges 10–80 - NCT07314580Recruiting
Transplanting premolars to replace lost front teeth in teens
This trial tests whether moving a back tooth (premolar) to replace a lost or damaged front tooth works well in young people aged 7–15. It aims to help avoid bridges or implants by using the patient's own tooth.
Barcelona, BarcelonsAges 7–15 - NCT04120688Recruiting
Transplanting a natural tooth using a 3D planned approach
This trial looks at a way to move a patient’s own tooth (or a prepared tooth) to replace a missing or damaged one, using a 3D plan to guide the procedure. It may help restore chewing ability and appearance by using a tooth-shaped replacement tailored for the patient.
Turku, TurkuAges 9–23 - NCT07632443Recruiting
Testing temporary dental crowns and bridges made of PMMA
This study tests the safety and performance of ON DENT® temporary dental crowns and bridges made from a tooth-colored plastic material called PMMA. If you need a temporary crown or bridge while waiting for a permanent restoration, this trial may help determine how well these temporary options work.
IzmirAges 18 years+ - NCT07011303Enrolling by invitation
Using your own blood clot to help bone heal after tooth extraction
This study tests whether placing a special clot made from your own blood (called Platelet Rich Fibrin) into the socket after a tooth extraction helps the bone heal better for a future dental implant.
Tokat ProvinceAges 18–40 - NCT07177521Recruiting
Short dental implants after tooth extraction
This study tests whether short implants placed right after a tooth is pulled are stable and work well. It may be a good option if you need a single back tooth replaced and are generally healthy.
BariAges 18–75 - NCT07580495Recruiting
Collagen Membrane to Preserve Jaw Bone After Tooth Extraction
This study tests whether a collagen membrane (a thin, natural material) placed after a tooth extraction helps preserve the jaw bone. Keeping bone healthy can make future tooth replacement easier and more successful.
Pittsburgh, PennsylvaniaAges 18–80 - NCT07508033RecruitingPhase 1/Phase 2
Stem cell exosomes vs platelet-rich fibrin for socket healing
This trial tests whether stem cell exosomes (tiny healing particles from stem cells) work better than platelet-rich fibrin (a blood-derived clot) to help a tooth socket heal after extraction. It may help if you need a single front or premolar tooth removed and are generally healthy.
Tanta, Gharbia GovernorateAges 20–45 - NCT07718932Recruiting
Healing gel for wisdom tooth extraction recovery
This trial tests a regenerative gel placed in the socket after wisdom tooth removal to improve healing. It may reduce pain, swelling, and speed up recovery.
ThessalonikiAges 18–35 - NCT07483086Recruiting
Implant position for thin gum patients
This study tests whether the vertical position of a dental implant affects bone loss around it, specifically for people with thin gums. If you are missing a single upper front tooth or premolar, you may be a candidate.
CairoAges 18 years+ - NCT07714265Recruiting
Gum thickening around dental implants: comparing three methods
This trial compares three techniques to thicken gum tissue around a single dental implant in the back of the lower jaw. It may help if you have thin gums and need a dental implant.
CairoAges 20 years+ - NCT07568249Recruiting
How full arch dental implants affect your quality of life
This study looks at how getting a full set of dental implants (for a whole upper or lower jaw) affects your oral health and quality of life. Researchers want to see how your experience changes from before treatment through recovery.
Lisbon, Lisbon DistrictAges 18 years+ - NCT04605445Recruiting
One vs two dentist visits for infected root canals
This study compares whether treating an infected, dead tooth in one visit works as well as using two visits. It may help you and your dentist choose the simplest schedule while still clearing infection and supporting healing.
Vaxjo, Kronoberg CountyAges 18 years+ - NCT06191107Recruiting
Partial dentures made of PEEK
This trial tests partial dentures made of a special plastic (PEEK). It may be an option if you need a removable partial denture held by clasps.
HeidelbergAges 18–75 - NCT06287346Recruiting
Comparing one-piece vs two-piece ceramic dental implants
This study tests two types of ceramic (metal-free) dental implants in people who are missing teeth and may have metal allergies. The implants are followed for 5 years to see how well they work and how safe they are.
Boulder, ColoradoAges 18 years+ - NCT06571812Recruiting
Study of the TSX dental implant system (Xpresso)
This trial tests a new dental implant system (called TSX Xpresso) for replacing a single missing tooth, either right after pulling the tooth or after the gum has healed. It may be a good option if you need a dental implant and want to see how this system works.
Columbus, OhioAges 18 years+ - NCT06576284Recruiting
Tracking custom dental implant performance over 3 years
This study follows people who already received a personalized dental implant designed by computer. Researchers want to see how the implant performs over 3 years, measuring things like how well it works and if any problems come up.
São PauloAges Any age - NCT06654141Recruiting
Healing time and tooth socket preservation after molar extraction
This study looks at how different healing times affect the success of preserving the bone where a molar is removed due to gum disease. It aims to find the best wait time before placing a dental implant.
ShanghaiAges 18 years+ - NCT06783595Recruiting
Gum changes after removing temporary implant crown
This study looks at how the gums around a dental implant change after the temporary crown is removed, in the front upper teeth area. It helps dentists understand healing and gum shape to improve future implant treatments.
Loma Linda, CaliforniaAges 18 years+ - NCT06870955Recruiting
Study of biomimetic abutments for dental implants
This trial tests a new type of abutment (the connector piece between an implant and a crown) that is designed to look and function more like a natural tooth root. It may help people who have a single missing tooth and need a second surgery to uncover their implant.
Fuzhou, FujianAges 25–65 - NCT07280260RecruitingPhase 4
Testing a new dental implant system for replacing a missing back tooth
This trial tests the Nobel N1 dental implant system in people missing a single back tooth. It aims to see how well the implant works when a replacement tooth is placed right away.
New Orleans, LouisianaAges 18 years+ - NCT07315607Recruiting
Study of same-day implant crowns made with digital planning
This trial tests a new digital planning and guided surgery method for placing and placing a temporary crown on a dental implant right after tooth removal. It aims to see how accurate these same-day, screw-retained crowns are, which could mean fewer visits and faster results for you.
Madrid, MadridAges 18 years+ - NCT07337057Recruiting
Standardized dental implant outcomes
This study is creating a standard way to measure the success of dental implants. It is for people who need a new implant or a replacement implant, and who do not have major health or mouth problems that would complicate the procedure.
Rotterdam, South HollandAges 18–75
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Common questions
- Are there clinical trials for tooth loss?
- Yes. Clin2 currently lists 35 recruiting tooth loss studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tooth loss trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tooth loss trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.