Clinical trials
Tooth Loss clinical trials
Below are recruiting tooth loss clinical trials, each written for real people, not researchers. We’re tracking 37 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04281056Recruiting
Tooth loss and dentures: taste and food preferences
This study looks at how losing teeth and wearing dentures affects your mouth sensations and your food choices. It compares people who are fully without teeth (and use dentures) with people who still have their natural teeth.
ParisAges 18–79 - NCT07812883Recruiting
Preserving jawbone after tooth removal
This study tests a technique to preserve the jawbone after a tooth is removed, so there is enough bone left to place a dental implant later. It may help people who need a tooth extraction and want to get a dental implant in the future.
Santiago, Santiago MetropolitanAges 18 years+ - NCT07393997Recruiting
Tooth transplant with platelet-rich fibrin for young patients
This trial tests a tooth transplant method that uses a healthy tooth from elsewhere in your mouth to replace a missing tooth. A special protein-rich material (platelet-rich fibrin) is placed around the new tooth to help it heal and grow roots. It's designed for children, teens, and young adults who cannot get dental implants.
BariAges 10–80 - NCT07314580Recruiting
Transplanting premolars to replace lost front teeth in teens
This trial tests whether moving a back tooth (premolar) to replace a lost or damaged front tooth works well in young people aged 7–15. It aims to help avoid bridges or implants by using the patient's own tooth.
Barcelona, BarcelonsAges 7–15 - NCT07632443Recruiting
Testing temporary dental crowns and bridges made of PMMA
This study tests the safety and performance of ON DENT® temporary dental crowns and bridges made from a tooth-colored plastic material called PMMA. If you need a temporary crown or bridge while waiting for a permanent restoration, this trial may help determine how well these temporary options work.
IzmirAges 18 years+ - NCT04120688Recruiting
Transplanting a natural tooth using a 3D planned approach
This trial looks at a way to move a patient’s own tooth (or a prepared tooth) to replace a missing or damaged one, using a 3D plan to guide the procedure. It may help restore chewing ability and appearance by using a tooth-shaped replacement tailored for the patient.
Turku, TurkuAges 9–23 - NCT07801573Recruiting
Immediate dental implants with custom healing caps for back teeth
This trial tests placing a dental implant right after removing a damaged back tooth, using a custom healing cap. It may help people who need a tooth extraction and want a faster path to a replacement tooth.
PlovdivAges 18 years+ - NCT07011303Enrolling by invitation
Using your own blood clot to help bone heal after tooth extraction
This study tests whether placing a special clot made from your own blood (called Platelet Rich Fibrin) into the socket after a tooth extraction helps the bone heal better for a future dental implant.
Tokat ProvinceAges 18–40 - NCT07177521Recruiting
Short dental implants after tooth extraction
This study tests whether short implants placed right after a tooth is pulled are stable and work well. It may be a good option if you need a single back tooth replaced and are generally healthy.
BariAges 18–75 - NCT07580495Recruiting
Collagen Membrane to Preserve Jaw Bone After Tooth Extraction
This study tests whether a collagen membrane (a thin, natural material) placed after a tooth extraction helps preserve the jaw bone. Keeping bone healthy can make future tooth replacement easier and more successful.
Pittsburgh, PennsylvaniaAges 18–80 - NCT07508033RecruitingPhase 1/Phase 2
Stem cell exosomes vs platelet-rich fibrin for socket healing
This trial tests whether stem cell exosomes (tiny healing particles from stem cells) work better than platelet-rich fibrin (a blood-derived clot) to help a tooth socket heal after extraction. It may help if you need a single front or premolar tooth removed and are generally healthy.
Tanta, Gharbia GovernorateAges 20–45 - NCT07718932Recruiting
Healing gel for wisdom tooth extraction recovery
This trial tests a regenerative gel placed in the socket after wisdom tooth removal to improve healing. It may reduce pain, swelling, and speed up recovery.
ThessalonikiAges 18–35 - NCT07483086Recruiting
Implant position for thin gum patients
This study tests whether the vertical position of a dental implant affects bone loss around it, specifically for people with thin gums. If you are missing a single upper front tooth or premolar, you may be a candidate.
CairoAges 18 years+ - NCT06287346Recruiting
Comparing one-piece vs two-piece ceramic dental implants
This study tests two types of ceramic (metal-free) dental implants in people who are missing teeth and may have metal allergies. The implants are followed for 5 years to see how well they work and how safe they are.
Boulder, ColoradoAges 18 years+ - NCT06191107Recruiting
Partial dentures made of PEEK
This trial tests partial dentures made of a special plastic (PEEK). It may be an option if you need a removable partial denture held by clasps.
HeidelbergAges 18–75 - NCT07801339Enrolling by invitation
Dental implants for patients 80 and older
This study looks at placing dental implants right after removing a tooth in people who are 80 or older. It aims to see how well these implants work in very elderly patients and if they can improve quality of life.
Gotemba, ShizuokaAges 80 years+ - NCT07727655Recruiting
Enamel protein for immediate lower molar implants
This trial is testing a special enamel protein (Emdogain) placed around a new dental implant right after removing a broken lower molar. It aims to see if this helps the implant heal better.
Al Mansurah, Dakahlia GovernorateAges 18–45 - NCT07714265Recruiting
Gum thickening around dental implants: comparing three methods
This trial compares three techniques to thicken gum tissue around a single dental implant in the back of the lower jaw. It may help if you have thin gums and need a dental implant.
CairoAges 20 years+ - NCT07633665Recruiting
Safety and effectiveness study of dental implants
This study tests two types of dental implants (BIODENTOSS® and DWC®) to see how well they work and how safe they are in patients who need tooth replacement. If you have a missing tooth and want an implant, this study will track how your implant performs over time.
KonyaAges 18 years+ - NCT06576284Recruiting
Tracking custom dental implant performance over 3 years
This study follows people who already received a personalized dental implant designed by computer. Researchers want to see how the implant performs over 3 years, measuring things like how well it works and if any problems come up.
São PauloAges Any age - NCT07604142Enrolling by invitation
Donor bone to close sinus opening after tooth extraction
This trial tests using sterilized donor bone to repair a hole that opens into your sinus when a severely damaged upper back tooth is removed. The goal is to rebuild the bone so a dental implant can be placed safely later.
TantaAges 20 years+ - NCT07568249Recruiting
How full arch dental implants affect your quality of life
This study looks at how getting a full set of dental implants (for a whole upper or lower jaw) affects your oral health and quality of life. Researchers want to see how your experience changes from before treatment through recovery.
Lisbon, Lisbon DistrictAges 18 years+ - NCT07518615Recruiting
Safety and Effectiveness of Guided Dental Implant Surgery System
This trial tests a new computer-guided system (Straumann Dynamic Navigation Falcon) that helps dentists place dental implants more precisely. If you need one or more dental implants and have healthy gums and jaw, this study may help determine if this guided approach is safe and works well.
GhentAges 18 years+ - NCT07484685Recruiting
Earlier implant placement after tooth preservation
This study tests if placing a dental implant sooner (about 6-8 weeks after tooth removal and socket preservation) works well with a specific implant type. It is for people who need to replace a single front tooth, canine, or premolar and have good bone and gum health.
Guayaquil, GuayasAges 18 years+
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Common questions
- Are there clinical trials for tooth loss?
- Yes. Clin2 currently lists 37 recruiting tooth loss studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tooth loss trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tooth loss trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.