Clinical trials
Transgender clinical trials
Below are recruiting transgender clinical trials, each written for real people, not researchers. We’re tracking 44 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06177600Recruiting
TransHealthGUIDE: Health help for gender-diverse young adults
This study aims to improve healthcare for gender-diverse young adults (ages 18-29) and their caregivers. It involves a program to support transgender and nonbinary health and will take place online.
Boston, MassachusettsAges 18–29 - NCT05318755Recruiting
Gender-affirming hormone therapy study for adults starting care
This study looks at starting gender-affirming hormone therapy (GAHT) for transgender people who have never had these treatments before. It may help you learn whether this approach is safe and effective for your goals as you begin care.
Beijing, Beijing MunicipalityAges 18–40 - NCT06202898Recruiting
Study helping transgender women access HIV prevention (PrEP)
This study helps transgender women who are not regularly using PrEP (a daily pill to prevent HIV) get access to HIV prevention services. It uses a smartphone to take pictures and connect with support.
Orlando, FloridaAges 18 years+ - NCT06487754Recruiting
Chronic pelvic pain in trans people on testosterone therapy
This study explores why some trans masculine people develop new or worsening pelvic pain after starting testosterone therapy. Researchers want to understand your experience through interviews.
Saint-Martin-d'HèresAges 18 years+ - NCT07512856Recruiting
Support Service for Transgender People Using Substances
This study tests a new support program designed specifically for transgender people who use drugs or engage in chemsex (using drugs during sexual activity). The program aims to reduce health risks and provide safer, more culturally respectful care.
Pathum Wan, BangkokAges 18 years+ - NCT07505875Recruiting
Study to create transgender-friendly services for chemsex support
This study aims to develop healthcare services tailored to transgender people regarding chemsex (using drugs during sex). Researchers will interview participants to understand their needs and experiences.
Pathum Wan, BangkokAges 18 years+ - NCT06832514RecruitingPhase 4
Gender and immune response to meningitis B vaccine
This study tests how well the meningitis B vaccine works in transgender and cisgender people. It aims to understand if sex and gender affect immune responses.
GhentAges 18–50 - NCT06774053Recruiting
The SPECTRA study for transgender and gender diverse people
This study follows transgender and gender diverse people of all ages 16 and older to learn more about their health and well-being over time. It is for those who have a diagnosis of gender incongruence and are either starting, continuing, or have stopped gender affirming therapy.
BaselAges 16 years+ - NCT06733415Enrolling by invitation
Hormone therapy and energy changes in transgender people
This study looks at how starting gender-affirming hormone therapy changes the way your body uses energy. It might help explain weight and metabolism changes some people notice during treatment.
Tel AvivAges 17 years+ - NCT06436560Enrolling by invitation
Support for transgender and non-binary people seeking vaginoplasty
This study tests a virtual peer support program for transgender and non-binary people who are planning to have vaginoplasty. It aims to see if talking with a trained peer can help with the process.
San Francisco, CaliforniaAges 18 years+ - NCT05927350Recruiting
Transgender and gender-diverse teens research participation
This study is looking for teens ages 15 to 21 who identify as transgender or gender-diverse (their gender identity is different from the sex they were assigned at birth). Your participation may help researchers better understand and support transgender and gender-diverse youth.
Richmond, VirginiaAges 15–21 - NCT04028219Recruiting
Study for people transitioning gender-affirming care
This study looks at people who are preparing to start gender-affirming hormone treatment. It may help researchers understand what support is needed before hormones begin.
Frankfurt am Main, HesseAges 18 years+ - NCT06530992Recruiting
Tucking and semen quality in adult trans women
This study looks at whether tucking affects semen quality in adult transgender women who are about to start or are on hormone therapy. The results could help patients understand how tucking might impact their fertility options.
InnsbruckAges 18–50 - NCT07746999Enrolling by invitation
Liver health study for transgender adults
This study looks at liver health in transgender individuals to better understand and improve care. You may join if you are 18 or older and can read and write in English.
Newark, New JerseyAges 18 years+ - NCT06639763Recruiting
Erectile aid use after gender-affirming surgery
This study looks at how transgender men and their partners use erectile aids after phalloplasty or metoidioplasty. It hopes to improve sexual health and satisfaction after surgery.
Ghent, East-FlandersAges 18 years+ - NCT06639776Recruiting
Sexual function after erectile implant in transgender people
This study looks at how well erection prostheses (implants that help with erections) work for transgender people after phalloplasty surgery. It aims to understand sexual functioning for both you and your partner.
Ghent, East-FlandersAges 18 years+ - NCT07706322Recruiting
Sexual assault prevention program for trans and nonbinary undergrads
This study tests a program to help prevent sexual assault that's designed specifically for trans and nonbinary college students. You'll join with a partner or be paired with another student, and take part in group sessions over Zoom.
College Park, MarylandAges 18–25 - NCT07624747Recruiting
Brain Health Study for Transgender Adults Starting Hormone Therapy
This study looks at how gender-affirming hormone therapy affects brain health and function in transgender adults. Researchers want to understand the effects of these hormones on the brain before and after treatment begins.
Madison, WisconsinAges 18–45 - NCT07509853Recruiting
Pleasure-Focused Harm Reduction for Chemsex and Substance Use
This study explores how adding conversation about sexual pleasure to harm reduction services can help men who have sex with men and transgender persons who use drugs during sex or use other substances. If you join, you may learn new ways to reduce risks while still enjoying your sex life.
Pathum Wan, BangkokAges 18 years+ - NCT07509827Recruiting
App-based program to help prevent HIV and reduce stigma
This study tests a mobile health program to help young transgender women prevent HIV and cope with stigma. Participants use an app and are not yet taking PrEP daily or have trouble sticking with it.
Bangkok, BangkapiAges 18–29 - NCT07466069Recruiting
Healthy lifestyle program for transgender teens
This trial tests a lifestyle program designed to prevent obesity and eating disorders in transgender and gender-diverse adolescents. It aims to support healthy habits and well-being during a critical developmental stage.
São Paulo, São PauloAges 10–14 - NCT06656676Recruiting
WePrEP: HIV prevention tool for transgender women
This study is creating a decision-making tool to help transgender women choose the right PrEP (HIV prevention pill) for them. It is looking for transgender women in Denver who are HIV-negative and interested in learning more about PrEP, as well as healthcare providers who help transgender women decide about PrEP.
Sheridan, ColoradoAges 18–65 - NCT05169762Recruiting
Hormone feminizing treatment for transgender and non-binary people
This study looks at feminizing gender-affirming treatment (hormones) in transgender women and non-binary people. It may help improve how this type of treatment is provided and evaluated for safety and effectiveness.
OdenseAges 18 years+ - NCT07252687Recruiting
How Gender-Affirming Care Affects Breast Perception in Trans Men
This study looks at how gender-affirming treatments (like hormone therapy or chest surgery) affect how trans men feel about their chest. It aims to help understand the best timing for these treatments.
InnsbruckAges 16 years+
Hear when a new Transgender trial opens
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Common questions
- Are there clinical trials for transgender?
- Yes. Clin2 currently lists 44 recruiting transgender studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a transgender trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a transgender trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.