Clinical trials
Traumatic Stress clinical trials
Below are recruiting traumatic stress clinical trials, each written for real people, not researchers. We’re tracking 266 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06162741Recruiting
Brief mindfulness training for Veterans in primary care
This study tests whether brief mindfulness training offered in VA primary care can help Veterans with symptoms of PTSD, depression, or anxiety. It aims to see if this approach works well in everyday clinic settings.
Phoenix, ArizonaAges 18 years+ - NCT06194851RecruitingPhase 2
Oxytocin nasal spray plus couples therapy for Veterans with PTSD
This study tests whether a nasal spray of oxytocin (a natural hormone) can boost the effects of a brief couples therapy for Veterans with PTSD. You and your partner would receive either the spray or a placebo (inactive spray) during therapy sessions to see if it helps reduce PTSD symptoms and improve relationship satisfaction.
San Diego, CaliforniaAges 18 years+ - NCT06203106Recruiting
NYSCF Scientific Discovery Biobank
This study collects blood, saliva, or skin samples from people with certain neurological conditions and from healthy volunteers to help researchers better understand and find treatments for these diseases.
New York, New YorkAges 4 weeks+ - NCT06266364Recruiting
Vagus nerve stimulation for treatment-resistant PTSD
This study tests if stimulating the vagus nerve with an implanted device can help adults with chronic PTSD who haven't gotten better with standard treatments. You would have the device implanted and then follow the study plan for several months.
Austin, TexasAges 22–79 - NCT06273527RecruitingPhase 2/Phase 3
Thinking skills training for mood and anxiety
This study tests whether a computerized training program can help people with mood, anxiety, or trauma-related disorders who struggle with repetitive negative thinking. If you are an outpatient and can have an MRI, this may be a good fit.
San Diego, CaliforniaAges 21–55 - NCT06310109Recruiting
PICU Diaries to Support Children and Families
This study tests whether a special diary, kept by families during the PICU stay, helps children and their parents cope better after leaving the hospital. It is for children who needed a breathing machine for more than 48 hours.
RomeAges Up to 19 years - NCT06332209Recruiting
Telehealth vs. in-person therapy for trauma in Puerto Rican youth
This trial compares two ways of giving a type of therapy called Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) to children and teens in Puerto Rico who have been through a traumatic event and have post-traumatic stress symptoms. One group receives therapy in person at a clinic, and the other group receives therapy through video calls (telehealth), to see which works better.
Charleston, South CarolinaAges 7–18 - NCT06335407RecruitingPhase 1
Testing a new under-the-tongue med for alcohol use and trauma
This study tests a new sublingual (under-the-tongue) medication for people with alcohol use disorder who have also had a traumatic life event. It aims to see if the medication can help reduce drinking and related symptoms.
West Haven, ConnecticutAges 21–65 - NCT06386003RecruitingPhase 2
Psilocybin and talk therapy for chronic PTSD
This trial tests whether a medication called psilocybin (the active ingredient in magic mushrooms) can help people with long-term PTSD when combined with a specific type of talk therapy. The goal is to see if this approach reduces PTSD symptoms more than therapy alone.
Toronto, OntarioAges 18–65 - NCT06394284RecruitingPhase 3
MDMA therapy for PTSD in male Israeli veterans
This study tests whether MDMA (the drug in Ecstasy) can help male Israeli veterans with PTSD feel better, especially if their symptoms are related to moral injury. It involves therapy sessions and monitoring to see how the drug affects your brain and emotions.
JerusalemAges Any age - NCT06419959Recruiting
NightWare watch for better sleep and heart health in veterans with PTSD
This study tests if a special watch (NightWare) can help veterans with PTSD who have nightmares sleep better and improve heart health. The watch vibrates gently during nightmares to reduce them without waking you up.
Aurora, ColoradoAges 22–88 - NCT06479447Recruiting
Patient-reported PTSD screening study
This trial is testing a simple way to check for PTSD symptoms using patient-reported questionnaires. It aims to help people who haven't been screened recently get the care they need.
Chicago, IllinoisAges 18 years+ - NCT06548126Recruiting
Online parenting program for displaced families
This trial tests an online parenting program for caregivers who have experienced forced displacement. It aims to support families with children aged 6 to 12 by teaching positive parenting skills.
Tempe, ArizonaAges 18 years+ - NCT06589505RecruitingPhase 2/Phase 3
Software app for treating PTSD
This trial is testing a software program (like an app) designed to help treat PTSD. It may be an option if your PTSD is related to a past traumatic event and you haven't already tried several trauma-focused therapies.
Yamanashi, HokkaidoAges 18–65 - NCT05732155RecruitingPhase 2
MDMA-assisted therapy for Israeli veterans with PTSD
This study tests whether MDMA (the active ingredient in Ecstasy) given in therapy sessions can help Israeli special forces veterans with PTSD and moral injury. Participants will receive MDMA alongside talk therapy to see if it reduces symptoms.
AfulaAges 18 years+ - NCT06635486Recruiting
Mental health support for Venezuelans in Lima
This study offers mental health support to Venezuelan adults living in Lima who are feeling anxious, depressed, or have experienced trauma. It will check if you have signs of depression, anxiety, or post-traumatic stress and provide help if you do.
LimaAges 18 years+ - NCT06642636Recruiting
Virtual reality before ICU for lung transplant patients
This study tests if a virtual reality experience before entering the ICU can help prepare you. It is for people waiting for a lung transplant.
Rotterdam, South HollandAges 18–71 - NCT06679062RecruitingPhase 2
Suvorexant for alcohol use disorder and PTSD
This study tests whether the sleep medication suvorexant can help people with both alcohol use disorder and PTSD. If you're struggling with drinking, PTSD symptoms, and poor sleep, this trial may offer a new treatment option.
Los Angeles, CaliforniaAges 21–65 - NCT06689254RecruitingPhase 2
Testing mifepristone for hard-to-treat PTSD in Dutch adults
This study tests a new medicine (mifepristone) to see if it helps people with PTSD that hasn't improved after standard treatments. You must be fluent in Dutch and have tried at least two PTSD treatments, including trauma-focused therapy.
Amsterdam, North HollandAges 18 years+ - NCT06700590Recruiting
Intensive PTSD treatment for first-time patients
This study tests an intensive treatment program for adults with PTSD from multiple traumatic events. It may help if you are seeking treatment for the first time and are currently employed or on sick leave for less than two years.
Diemen, North HollandAges 18 years+ - NCT06733376Recruiting
PTSD treatment options study
This study tests different types of talk therapy for PTSD, like CPT, PE, and STAIR. It aims to find which treatment works best for people with PTSD.
Chicago, IllinoisAges 18 years+ - NCT06773338Recruiting
Can playing Tetris improve mental health for migrants?
This study tests if playing the game Tetris can help reduce stress and improve mood for Arabic-speaking immigrants who have applied for asylum. You would play Tetris a few times and report how you feel.
The Hague, NLAges 18 years+ - NCT06806267Recruiting
VR therapy with brain stimulation for PTSD in Ukrainians
This study tests if combining virtual reality therapy with a gentle brain stimulation technique (tDCS) can help treat PTSD symptoms in Ukrainian veterans and civilians. It may offer a new way to process traumatic memories.
BerlinAges 18–75 - NCT06834867Recruiting
Family support to reduce depression and address partner violence in Nepal
This trial tests a program for married women, their husbands, and mothers-in-law to reduce depression and stop intimate partner violence. It includes counseling and support for families who want to stay together.
Kathmandu, BagmatiAges 15–24
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Common questions
- Are there clinical trials for traumatic stress?
- Yes. Clin2 currently lists 266 recruiting traumatic stress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a traumatic stress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a traumatic stress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.