Clinical trials
Treatment as Usual clinical trials
Below are recruiting treatment as usual clinical trials, each written for real people, not researchers. We’re tracking 315 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06236347Enrolling by invitation
Rural COPD study using e-visits for smokers
This study tests whether online e-visits can help rural smokers without COPD quit smoking. It uses smartphone tools and mailed devices to track progress remotely.
Charleston, South CarolinaAges 40 years+ - NCT05748730Recruiting
Care team support program for teens at risk of depression
This study tests an “integrated care” program that supports teens who are dealing with depression symptoms or recent suicidal thoughts. It also involves a parent or caregiver to help improve support at home and connect teens to the right help.
Gibbsboro, New JerseyAges 12–18 - NCT05706376Recruiting
Family support program for Palestinian teens and parents
This study tests an evidence-based family support program that involves parents and adolescents together. It may help families improve support and wellbeing by giving structured guidance and group-based sessions.
Notre Dame, IndianaAges 12–75 - NCT05287711Recruiting
Motivational alcohol support to help prevent partner violence
This study tests an extra (adjunct) counseling approach to reduce harmful alcohol use in Veterans enrolled in the Strength at Home program. The goal is to help prevent intimate partner violence (IPV), especially when alcohol is involved.
Boston, MassachusettsAges 18 years+ - NCT05078970Recruiting
Teen suicide intervention study for high-risk times
This study tests a suicide intervention approach for teens who are having suicidal thoughts or behaviors and are currently in an emergency or hospital setting. It may help you and your care team better support teens during the most risky period.
Columbus, OhioAges 11–17 - NCT03769259Enrolling by invitation
Therapy for recent suicidal thoughts or attempts
This study tests a brief counseling approach based on cognitive behavioral therapy to help people who are dealing with suicidal thoughts or a recent suicide attempt. It’s offered in outpatient care and aims to see whether this shorter therapy works for improving safety and coping.
Jacksonville, North CarolinaAges 18 years+ - NCT06454136Enrolling by invitation
App-based support for teens after a suicide attempt
This trial tests a mobile app designed to help teenagers who have recently been hospitalized after a suicide attempt or serious suicidal thoughts. The goal is to see if the app can provide extra support and reduce future suicide attempts.
Hartford, ConnecticutAges 13–17 - NCT05528926Recruiting
Resist irritability: a trial for children with ongoing behavior issues
This trial tests a program meant to reduce long-lasting irritability in children and teens who have conditions like ADHD, oppositional behavior, disruptive behavior, mood/anxiety problems, or DMDD. It includes children whose parents rate irritability as at least moderately severe and who have had symptoms for 6 months or more.
MontpellierAges 6–15 - NCT00601939Recruiting
Group therapy sessions for suicidal women in abusive relationships
This study looks at whether empowerment-focused group sessions can help African-American women who are dealing with both abuse and recent suicidal thoughts or a suicide attempt. It aims to improve coping and support by offering structured group sessions through Grady Health System.
Atlanta, GeorgiaAges 18–64 - NCT06353711Recruiting
Caring Connections youth suicide detection and support
This study looks at better ways to find and help youth who are thinking about suicide or hurting themselves, especially those who have had trouble getting mental health services. It uses a team approach to connect youth with care and support.
Charlotte, North CarolinaAges 13 years+ - NCT06831942Recruiting
Suicide prevention counseling for adults 65 and older
This study tests a short counseling program for older adults (65+) who have recently attempted suicide or had serious suicidal thoughts. The program is designed to help reduce the risk of future suicide attempts. It is offered alongside your regular mental health care.
BoråsAges 65 years+ - NCT06281184Enrolling by invitation
Long-term follow-up of methotrexate for hand osteoarthritis
This study follows up on people who took part in the MERINO trial to see if methotrexate has lasting benefits for hand osteoarthritis. It aims to understand how the drug affects pain and joint health over 30 months.
OsloAges 18 years+ - NCT07510373Recruiting
Helping patients cut back on opioids after orthopedic surgery
This trial tests a program to help patients safely reduce their opioid pain relievers after leaving the hospital following orthopedic surgery. It is designed for people who are new to opioids and want to avoid long-term use.
The Bronx, New YorkAges 18 years+ - NCT06309329Enrolling by invitation
Strength at Home for Veteran Parents: A Study
This study tests a program called Strength at Home for veteran parents. It helps improve parenting and reduce stress for veterans with PTSD who have a child between 3 and 12 years old.
Temple, TexasAges 18 years+ - NCT05691647Recruiting
Testing timing-based treatment for a new depressive episode
This trial studies whether “chronotherapy” (carefully timing daily activities/therapies) can help people with a new moderate to severe depression episode. You may be eligible if your depression is recent and fairly severe, and if your daily schedule can support the timing plan.
TrondheimAges 18–100 - NCT07132099Recruiting
Suicide prevention therapy for recent attempt survivors
This trial tests two talk therapies, ASSIP and ACT, to help people who have recently attempted suicide. It aims to find which approach better reduces future risk.
Eslamshahr, Tehran ProvinceAges 18 years+ - NCT07486037Recruiting
Exercise program for African American Alzheimer's caregivers
This study is for African American caregivers of someone with Alzheimer's or a related dementia. It explores whether a gentle exercise program can help you feel better and manage the stress of caregiving.
Indianapolis, IndianaAges 18–99 - NCT06620302RecruitingPhase 1/Phase 2
Adding DT2216 to chemo for relapsed solid tumors and FLC
This trial is testing whether adding a new drug, DT2216, to standard chemotherapy can help treat solid tumors (not starting in the brain) or fibrolamellar carcinoma (FLC) that have come back or not responded to treatment. It's for children, teens, and young adults (ages 1 to 39).
Birmingham, AlabamaAges 1–39 - NCT07404787Recruiting
Suicide prevention telehealth program for soldiers after hospital stay
This trial tests a telehealth case management program to help prevent suicide among soldiers recently discharged from a psychiatric hospital. If you are an active duty soldier who has been hospitalized for mental health reasons and have access to a phone and computer, this program may provide extra support during your recovery.
Bethesda, MarylandAges 18 years+ - NCT05884476Recruiting
Re-checking suicidal thoughts in Veterans during a study
This study looks at a way to re-evaluate and respond to suicidal thoughts in Veterans. It may help improve how support is offered when someone has had thoughts of suicide recently.
New Orleans, LouisianaAges 18 years+ - NCT06499740Recruiting
Supporting teens with suicidal thoughts in primary care
This study tests a short, supportive conversation for teens with suicidal thoughts that happens in their regular doctor's office. It aims to help teens and their families get the right care without needing a hospital stay.
Centralia, WashingtonAges 10 years+ - NCT05179655Recruiting
Parent-focused program for teens who self-harm
This trial studies a program for teens and their parents to help reduce non-suicidal self-injury. It may help families learn skills and support that prevent self-harm from continuing or worsening.
AalborgAges 13–17 - NCT07738081Enrolling by invitation
Testing a new therapy for substance use and emotional health
This trial is testing a new type of therapy (the Unified Protocol) that helps people who are in treatment for substance use and also have depression or anxiety. The goal is to see if this approach can improve emotional well-being and reduce substance use.
OviedoAges 18 years+ - NCT06460220Enrolling by invitation
Online support for parents of suicidal teens
This study tests an online course for parents of teenagers who have had suicidal thoughts, to help them better support their child. It is for families already getting care at a specific clinic at Nationwide Children's Hospital.
Columbus, OhioAges 10–18
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Common questions
- Are there clinical trials for treatment as usual?
- Yes. Clin2 currently lists 315 recruiting treatment as usual studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a treatment as usual trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a treatment as usual trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.