Clinical trials
Treatment as Usual clinical trials
Below are recruiting treatment as usual clinical trials, each written for real people, not researchers. We’re tracking 318 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05854667RecruitingPhase 2
High-dose lisdexamfetamine with rewards for meth use changes
This Phase 2 study tests high-dose lisdexamfetamine (a prescription stimulant) to help people reduce or stop methamphetamine use. It also uses “contingency management” (rewards tied to meeting goals) to encourage treatment participation and lower use.
Vancouver, British ColumbiaAges 18–55 - NCT06589544Recruiting
Virtual reality and brain stimulation for depression in cancer patients
This trial tests whether combining virtual reality therapy with transcranial magnetic stimulation (a non-invasive brain treatment) can help reduce depression in people who have had cancer in the last 5 years. It aims to improve mood without using medication.
Ferrara, FEAges 18–100 - NCT07080723RecruitingPhase 4
Guided treatment vs usual care for stubborn depression
This trial tests if using an algorithm to guide treatment works better than standard care for people whose depression hasn't gotten better with previous treatments. It aims to find a more effective approach for those with treatment-resistant depression.
AalborgAges 18–65 - NCT05681767Recruiting
Lifestyle coaching to support depression care in primary clinics
This trial studies whether motivational, multi-part lifestyle coaching can help adults with depression when they start treatment through a regular primary care clinic. If you’re eligible, the program may add supportive skills to help improve mood alongside usual care.
KuopioAges 18 years+ - NCT04746261Recruiting
Suicide care support program after a recent attempt
This study tests a brief, structured support program (ASSIP) for adults who have recently had a suicide attempt. It may help people cope better and stay connected to care after discharge from psychiatric or primary care.
LundAges 18 years+ - NCT06769282Recruiting
Preventing peer and dating violence for preteens in mental health programs
This study tests a program designed to teach preteens (ages 11–13) in intensive mental health treatment how to handle peer conflict and dating situations in a healthy way. It uses a trauma-informed approach to help build skills and reduce aggression.
Providence, Rhode IslandAges 11–13 - NCT07384273Recruiting
Online therapy for postpartum depression symptoms
This trial tests an internet-based therapy program (iCARE) to help new mothers manage symptoms of postpartum depression. It may be a good fit if you gave birth within the last 6 months and have been feeling down or depressed.
OdenseAges 18 years+ - NCT07502365Recruiting
Guaranteed income for young adults living with HIV
This study tests whether providing a basic income (no-strings-attached cash payments) can help young people with HIV stay healthy and engaged in care. If you qualify, you would receive regular payments and the research team would track your health over time.
Chicago, IllinoisAges 18–35 - NCT05965622Recruiting
Cost-effectiveness of ABFT for youth with suicidality
This study looks at whether ABFT (a family-based therapy) works well and is worth the cost for young adults who have strong suicidal thoughts. It also uses your family’s involvement to see how treatment affects safety and well-being over time.
Tongeren, LimburgAges 18–25 - NCT05948631Recruiting
Community support for children after partner violence
This trial tests a community-based program to help children who have been exposed to intimate partner violence (violence between caregivers/partners). It may help children and their families cope after traumatic experiences, and it includes sessions based on your family’s needs.
Houston, TexasAges 7–65 - NCT05034835Recruiting
Compression garments for arm nerve pain in CRPS
This study tests whether wearing a special compression sleeve or garment can reduce pain in people with complex regional pain syndrome (CRPS) affecting the arm. It’s looking at pain changes while making sure it’s safe for your skin and blood flow.
Ploemeur, Brittany RegionAges 18 years+ - NCT06494384Recruiting
Problem-solving treatment in community health centers
This trial tests if training therapists in a specific counseling method (problem-solving treatment) helps patients with depression. It's for adults who have depression and are seen at certain community health centers.
Portland, OregonAges 18 years+ - NCT07422519Recruiting
Virtual reality mindfulness for hard-to-treat depression
This study tests whether using a virtual reality mindfulness program, added to your usual depression care, can help people whose depression hasn't responded to standard treatments.
BarcelonaAges 18–74 - NCT06582901Recruiting
Support for youth at clinical high risk for psychosis in Tunisia
This study tests a support program for young people in Tunisia who show early signs of possible psychosis. It aims to help them before more serious symptoms develop.
TunisAges 14–28 - NCT05958875RecruitingPhase 4
Six-week medicine switch for schizophrenia after first treatment failure
This trial tests whether a more intensive medication approach for schizophrenia (or related conditions) helps people who didn’t improve on their first tried medicine. Participants will usually switch medicines and be compared against “treatment as usual.”
InnsbruckAges 18–70 - NCT05305794RecruitingPhase 3
Weekly Ozempic for insulin-dependent double diabetes
This trial tests whether a weekly injection called Ozempic (a GLP-1 medicine) can improve blood sugar control in adults who have type 1 diabetes plus higher-risk features for type 2 diabetes. If you qualify, the study will compare Ozempic against standard care to see if it helps your diabetes outcomes.
DijonAges 18 years+ - NCT06837662Recruiting
Counseling and peer support for opioid use disorder in primary care
This study tests whether adding counseling and peer support helps people with opioid use disorder and other medical problems stay in treatment. It is for patients seen at Central City Concern in Portland who are starting or restarting medication for opioid use disorder, or who are not yet on medication but want help.
Portland, OregonAges 18 years+ - NCT05597540RecruitingPhase 3
Shorter antibiotics for kidney transplant kidney infections
This study compares giving antibiotics for 7 days versus 14 days to treat acute kidney infections (pyelonephritis) in people with kidney transplants. It aims to see if the shorter course works just as well and is safer or easier to complete.
BordeauxAges 18 years+ - NCT05280132Recruiting
Testing quick tests to shorten antibiotics in severe COPD flare
This trial checks whether using fast test results (PCR from samples, a blood marker called procalcitonin, and sputum appearance) can safely reduce how long you need antibiotics during a severe COPD flare. It may help you receive fewer days of antibiotics while still controlling the infection risk.
ParisAges 18 years+ - NCT06755710Recruiting
Patient engagement study for PTSD treatment
This trial tests whether a program that helps people actively take part in their PTSD treatment leads to better outcomes. It is designed for adults with PTSD, including refugees, and aims to improve treatment engagement and results.
Ballerup Municipality, Capital RegionAges 18 years+ - NCT07710573Recruiting
Brief PTSD therapy compared to usual care for adults
This study tests a short, focused therapy (SEE FAR CBT) for adults with PTSD. It's a type of talk therapy that helps you process trauma, and the study wants to see if it works better than the usual care you would get.
Sha'ar HanegevAges 18 years+ - NCT07312760Recruiting
Talking therapy for existential distress in advanced cancer
This trial compares a short-term psychodynamic therapy (ORPHYS) with usual care for people with advanced cancer who are struggling with existential distress, such as loss of hope, fear of death, or loneliness. It aims to see if this therapy can help improve emotional well-being.
DüsseldorfAges 18 years+ - NCT06700590Recruiting
Intensive PTSD treatment for first-time patients
This study tests an intensive treatment program for adults with PTSD from multiple traumatic events. It may help if you are seeking treatment for the first time and are currently employed or on sick leave for less than two years.
Diemen, North HollandAges 18 years+ - NCT07194083Recruiting
Study on a treatment for wandering in children with autism
This trial tests a function-based treatment to reduce elopement (wandering away) in children with autism. It may help if your child wanders regularly and you are looking for a behavioral approach.
Atlanta, GeorgiaAges 4–12
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Common questions
- Are there clinical trials for treatment as usual?
- Yes. Clin2 currently lists 318 recruiting treatment as usual studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a treatment as usual trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a treatment as usual trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.