Clinical trials
Vaccine Response clinical trials
Below are recruiting vaccine response clinical trials, each written for real people, not researchers. We’re tracking 59 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04871932Recruiting
Study of immune response to a COVID-19 vaccine
This trial studies how your immune system responds after a COVID-19 vaccine. It uses detailed blood tests to understand what changes happen in your immune cells and may help researchers improve future vaccines.
ShanghaiAges 18–50 - NCT05562323Recruiting
Study of immune response after monkeypox vaccination
This is an observational study that follows adults after they get a monkeypox vaccine to learn how their immune system responds. The results may help researchers understand what types of protection the vaccine creates.
Badalona, BarcelonaAges 18 years+ - NCT04112355Enrolling by invitation
Tracking children’s immune response after routine vaccinations
This study measures how a child’s immune system responds after standard childhood vaccines, like DTaP-IPV/Hib, pneumococcal, MMR, varicella, flu, and COVID shots. It may help researchers better understand what a “healthy” immune response looks like after vaccination.
Rochester, MinnesotaAges 4 months–21 years - NCT06181656Recruiting
Pneumonia Vaccine Study for Esophageal and Liver Cancer Patients
This trial studies how well the pneumonia vaccine works in people with esophageal or liver cancer who have low white blood cell counts after chemoradiation. It aims to see if the vaccine can still protect them from infection.
Houston, TexasAges 18 years+ - NCT05384288Recruiting
How kids with blood cancers respond to the flu vaccine
This study looks at how children with blood cancers respond to the seasonal flu shot. It may help doctors understand what protection the vaccine provides for pediatric oncology patients.
Memphis, TennesseeAges Up to 18 years - NCT04128189RecruitingPhase 3
Shingrix vaccine for people waiting for a kidney transplant
This Phase 3 study tests whether the shingles vaccine Shingrix is safe and effective for adults with chronic kidney failure who are on the transplant waiting list. It aims to protect you from shingles while you may be dealing with transplant-related immune changes.
Aurora, ColoradoAges 18–70 - NCT01244802Enrolling by invitation
Study of immune memory after yellow fever vaccination
This study looks at how your immune system “remembers” the yellow fever vaccine over time. It may help researchers understand long-term immune protection and how it varies between people.
Decatur, GeorgiaAges 18 years+ - NCT05108818RecruitingPhase 4
Study immune responses after an flu shot in healthy adults
This study gives you a flu vaccine and measures how your immune system reacts, including both “blood immunity” and “cell immunity.” It’s for healthy adults and mainly aims to better understand how well flu vaccines work in people without major health issues.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07663032RecruitingPhase 1
Pan-Salmonella vaccine study for healthy young adults
This trial tests an experimental vaccine designed to protect against multiple types of Salmonella bacteria (which cause typhoid fever and other infections). It is given to healthy adults aged 18 to 45 to check safety and immune response.
BloemfonteinAges 18–45 - NCT05616546RecruitingPhase 4
Study of immune responses during and after flu infection
This study looks at how your immune system (your body’s infection-fighting system) responds during and around the time of a flu illness. It’s meant to help researchers better understand immune changes in healthy adults and may guide future flu care.
Atlanta, GeorgiaAges 18–64 - NCT07854392RecruitingPhase 4
Testing a new flu shot in healthy adults
This study tests a new flu vaccine to see how well it helps the body fight off the flu. It is for generally healthy adults aged 18 to 59 who have not had the flu recently.
Shaoxing, ZhejiangAges 18–59 - NCT06718127Recruiting
Study of immune response to yellow fever vaccine
This study looks at how your body's immune system responds to the yellow fever vaccine. It may help researchers understand how well the vaccine protects people.
ParisAges 18–65 - NCT02232191RecruitingPhase 2
Pneumonia vaccine immune response study after spleen injury
This trial studies how your immune system responds to a pneumonia (pneumococcal) vaccine after a spleen injury. It may help doctors better predict and improve protection in people recovering from splenic trauma.
Sacramento, CaliforniaAges 18–65 - NCT06624839RecruitingPhase 2
HPV vaccine study for people with and without HIV
This study tests how well the Gardasil 9 HPV vaccine works in people assigned male at birth, including those with HIV and those taking hormone therapy. Results could help protect against HPV-related cancers.
Washington D.C., District of ColumbiaAges 18–70 - NCT07851246RecruitingPhase 3
Flu vaccine study for adults 18 to 64
This study tests a new flu vaccine to see how well it protects adults aged 18 to 64. If you join, you'll get the vaccine and have some check-ups to see how your body responds.
Glendale, ArizonaAges 18–64 - NCT01720836RecruitingPhase 1/Phase 2
MUC1 peptide vaccine study for non-small cell lung cancer
This trial tests a vaccine made from a lung-cancer target (MUC1) to help your immune system recognize and fight the cancer. It is designed to measure immune response and safety, and it may help some people develop a stronger anti-cancer immune reaction.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07698600RecruitingPhase 1
Safety test of a new HIV vaccine in adults with or without HIV
This study tests a new RNA-based vaccine called BNT168 to see if it is safe and how the body responds to it. It is for healthy adults with or without HIV, and those with HIV will pause their regular treatment for a while during the study.
Houston, TexasAges 18–50 - NCT07527247RecruitingPhase 2
Testing a New Yellow Fever and Dengue Vaccine
This study tests a new vaccine designed to improve protection against yellow fever and dengue fever in healthy adults. Researchers want to see if this vaccine works better than existing ones and is safe.
SingaporeAges 21–59 - NCT07286370RecruitingPhase 2
Vaccine study for typhoid and salmonella in infants
This study tests a new vaccine that could protect infants against typhoid fever and a serious type of salmonella. If your baby is healthy and within the age range, they may be eligible to participate.
BanjulAges 1 month–6 months - NCT04706390Recruiting
Study compares immune response after COVID infection vs vaccination
This study looks at how your immune system responds after natural COVID-19 infection compared with after COVID vaccination. It may help researchers understand how well different experiences train the body’s defenses.
BergenAges 20–100 - NCT06855160RecruitingPhase 3
Chickenpox & MMR Vaccine Study for Healthy Toddlers
This study tests a new chickenpox vaccine combined with a standard MMR vaccine (measles, mumps, rubella) in healthy children aged 12-15 months. The goal is to see how well the vaccines work and how safe they are when given as a shot in the arm.
Tucson, ArizonaAges 1 year–1.3 years - NCT07769983Enrolling by invitationPhase 1
HIV vaccine study for people on effective treatment
This study tests a new vaccine designed to help your immune system fight HIV better. It is for people with HIV who are already on effective antiretroviral therapy and have a well-controlled virus. The goal is to see if the vaccine is safe and boosts your body's natural defenses.
Bern, Canton of BernAges 18 years+ - NCT07660198RecruitingPhase 3
Pneumonia vaccine catch-up study for kids and teens
This trial tests a catch-up pneumococcal vaccine for children and adolescents who may have missed some doses. It aims to see how safe and effective the vaccine is in healthy kids aged 15 months to 17 years.
Birmingham, AlabamaAges 1.3 years–17 years - NCT07464314RecruitingPhase 1
Testing a combined flu and COVID-19 mRNA vaccine in older adults
This trial is testing whether a new mRNA vaccine that targets both seasonal flu and COVID-19 is safe and creates a strong immune response. It may offer an easier way to protect against two illnesses with one shot.
Anniston, AlabamaAges 65–85
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Common questions
- Are there clinical trials for vaccine response?
- Yes. Clin2 currently lists 59 recruiting vaccine response studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vaccine response trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vaccine response trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.