Clinical trials
Systemic Inflammatory Response clinical trials
Below are recruiting systemic inflammatory response clinical trials, each written for real people, not researchers. We’re tracking 60 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05663216Recruiting
Study of fluid leaks in serious whole-body inflammation
This trial looks at what causes blood vessels to “leak” fluid during a dangerous whole-body inflammation response. It may help doctors understand why some people develop fluid buildup and aim for better monitoring and care in the ICU.
ParisAges 18 years+ - NCT06540027Enrolling by invitation
Minimally invasive surgery for rectal cancer inflammation
This study looks at how different types of surgery (open, laparoscopic, or robotic) affect inflammation throughout the body in people with rectal cancer. It may help doctors understand which approach is gentler on your immune system.
IstanbulAges Any age - NCT02055105Recruiting
Study tests a blood test pattern in children with sepsis
This trial studies how a specific pattern in blood (called “molecular fingerprinting”) changes in children with suspected or developing sepsis. The goal is to help doctors better recognize sepsis early and understand how it progresses, which may improve care.
Phoenix, ArizonaAges 1–18 - NCT06393062Recruiting
Urine test after kidney stone surgery
This trial checks whether a simple test on the first urine after kidney stone surgery can help find infections early. It only includes adults having a specific type of stone removal who are infection-free before surgery.
AdıyamanAges 18 years+ - NCT05927233RecruitingPhase 4
Methylprednisolone in children after open-heart surgery
This trial tests whether giving methylprednisolone (a steroid medicine) can lower the body’s inflammatory response in children during the first day after congenital open-heart surgery. It may help reduce harmful inflammation and improve recovery for some children undergoing their first surgery.
Karachi, SindhAges 1 month–18 years - NCT04033224Recruiting
Blood-filter treatments for ICU patients with kidney and organ failure
This trial tests a specific type of blood-filter treatment in critically ill ICU patients who have acute kidney injury and/or failure of other organs. It aims to see whether these filters can improve care by supporting kidney function and/or calming harmful inflammation.
Empoli, FirenzeAges Any age - NCT04580680Recruiting
Testing a blood-filter treatment in critically ill ICU patients
This study looks at an add-on blood-filter treatment used in the ICU to help remove harmful substances like waste products, inflammation signals, or toxins from the blood. Results may help doctors understand whether this approach improves care and how it should be used.
FlorenceAges Any age - NCT04669886Recruiting
Blood test before kidney stone surgery to predict infection risk
This study looks at a blood test done before percutaneous nephrolithotomy (PCNL), a procedure to remove kidney stones. The goal is to see whether results can predict who is more likely to develop infections or strong whole-body inflammation after surgery.
Miami, FloridaAges 18 years+ - NCT05172739RecruitingPhase 4
Opioid-free anesthesia during lung surgery for early lung cancer
This study tests whether an opioid-free pain/anesthesia plan during elective lung surgery can reduce surgical “stress” on the body and affect the immune system. You may be eligible if you have early-stage non-small cell lung cancer and are scheduled for a specific type of surgery (VATS lobectomy).
Heraklion, CreteAges 18–80 - NCT05969275RecruitingPhase 2
Cell therapy trial for infection-related septic shock in ICU
This Phase 2 trial tests an immune-boosting cell therapy (umbilical mesenchymal stromal cells) in people with septic shock—when infection causes dangerous stress on the heart and other organs. The goal is to see if this treatment can improve outcomes compared with standard care.
Ottawa, OntarioAges 18 years+ - NCT06052436RecruitingPhase 1/Phase 2
Treg cell therapy for COVID-19 and acute respiratory distress
This trial tests a new cell therapy using Treg cells from thymic tissue to calm an overactive immune response in severe COVID-19 and ARDS. It aims to improve breathing and reduce inflammation.
Madrid, MadridAges 18–65 - NCT06195267Recruiting
Sivelestat for lung protection during emergency aortic surgery
This study tests whether a drug called sivelestat can protect your lungs and other organs during emergency surgery for a very serious aortic tear. If you qualify, you would receive the drug or a placebo right before and after surgery.
BeijingAges 18–90 - NCT06542393RecruitingPhase 2
Blood management for anemic patients having bypass surgery
This trial tests a blood management strategy to help people with anemia who are having coronary artery bypass surgery (CABG). If you qualify, you may receive a treatment to improve your blood counts before surgery, which could reduce the need for transfusions.
São Paulo, São PauloAges 18–80 - NCT06684379RecruitingPhase 1/Phase 2
Two Doses of PRS CK STORM for Severe Viral Pneumonia
This study tests a new drug called PRS CK STORM to see if it can safely calm the body's overactive immune response (cytokine storm) in people with severe pneumonia from COVID-19, flu, or RSV who need oxygen. It aims to reduce inflammation and improve recovery.
Alcalá de Henares, MadridAges 18 years+ - NCT06695221Recruiting
Kefir trial for better health in Edmonton adults
This study tests if drinking kefir, a fermented dairy drink, can improve health in adults who are overweight or have high blood sugar or type 2 diabetes. It looks at how kefir might help with weight, blood sugar, and overall wellness.
Edmonton, AlbertaAges 24–70 - NCT06955975Recruiting
Pectin supplement for frailty in older adults
This study tests if daily pectin, a fiber found in fruits, can improve strength and health in older adults who are frail or pre-frail. It compares pectin to a placebo over time.
Nottingham, NottinghamAges 65 years+ - NCT01904188Recruiting
Rapid identification of infection germs and antibiotic resistance
This study tests whether a faster lab method can correctly identify the germ causing an infection and check which antibiotics may work, using samples taken in the emergency department. It may help doctors choose the right treatment sooner for people with serious suspected infection.
Lansing, MichiganAges 18 years+ - NCT06136793Enrolling by invitation
Healthy home habits for Chinese-heritage adults
This study tests a program to help Chinese-heritage adults with heart or diabetes conditions adopt healthier eating and lifestyle habits at home. It includes online resources and support to make lasting changes.
New Brunswick, New JerseyAges 30–70 - NCT06041581Enrolling by invitation
Insomnia treatment study for heart health
This study tests whether treating insomnia can help lower your risk for heart disease. If you have trouble sleeping and certain heart risk factors, you may be able to join.
Indianapolis, IndianaAges 40 years+ - NCT06286644Recruiting
Hops compounds and your immune system
This study looks at how compounds found in hops (used in beer) affect your immune system. If you are a healthy adult, you may join and help researchers learn more about how these natural substances work.
ViennaAges 18–70 - NCT07047053Recruiting
Shingles vaccine study for people with autoimmune diseases
This study looks at how well the shingles vaccine works in people with autoimmune inflammatory diseases. Researchers want to make sure the vaccine provides good protection for patients whose immune systems are affected by their condition or treatment.
ParisAges 18 years+ - NCT06745102Recruiting
Hop compounds for immune health in people with extra weight
This trial tests if compounds from hops can help the immune system of people who are overweight and showing early signs of metabolic issues like prediabetes, fatty liver, or mild high blood pressure.
ViennaAges 18–75 - NCT06599411Recruiting
Skin biomarkers for inflammatory disease treatment
This study looks for clues in your skin and blood that could predict how well you'll respond to treatments for conditions like eczema, psoriasis, or lupus. It aims to help doctors choose the best therapy for you.
ParisAges 18 years+ - NCT06842316Recruiting
Study on cannabis-like compounds for inflammatory arthritis
This trial tests whether plant-based compounds similar to cannabis (called phytocannabinoids) can help calm inflammation and improve immune function in people with certain types of arthritis or autoimmune diseases like lupus or Sjögren's disease. It aims to offer a new way to treat these conditions without the 'high' of marijuana.
OrléansAges 18 years+
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Common questions
- Are there clinical trials for systemic inflammatory response?
- Yes. Clin2 currently lists 60 recruiting systemic inflammatory response studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a systemic inflammatory response trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a systemic inflammatory response trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.