Clinical trials
Vaccine Response clinical trials
Below are recruiting vaccine response clinical trials, each written for real people, not researchers. We’re tracking 62 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05801978RecruitingPhase 4
How long a vaccine’s immune response lasts in adults
This study checks how long your body’s protection signals last after a vaccine. It may help researchers understand which vaccines give longer-lasting immune responses and who may need boosters.
Atlanta, GeorgiaAges 18–50 - NCT06821100RecruitingPhase 1
Thymalfasin to Boost COVID-19 Vaccine Response in Older Adults
This trial tests whether a drug called thymalfasin (thymosin alpha 1) can help older adults (65+) get a stronger immune response from their COVID-19 booster shot. It may be especially helpful for those whose immune systems have weakened with age.
Houston, TexasAges 65–100 - NCT06148025RecruitingPhase 4
Do antibiotics affect vaccine responses?
This study looks at whether taking a short course of antibiotics can change how your body responds to two vaccines (BCG and yellow fever). It may help researchers find ways to make vaccines work better.
Adelaide, South AustraliaAges 18–35 - NCT07177417RecruitingPhase 4
How the immune system responds to FluMist in the airways
This study tests how the immune system in your nose and airways responds to the FluMist nasal spray flu vaccine. It may help doctors understand why some people get better protection from the flu.
St Louis, MissouriAges 18–40 - NCT06635525Recruiting
How kidney failure affects your flu shot response
This study looks at how well the flu vaccine works in people with kidney failure who are on dialysis compared to healthy people. It will help doctors understand how kidney problems affect the body’s immune response to vaccination.
MilanAges 18–70 - NCT06832514RecruitingPhase 4
Gender and immune response to meningitis B vaccine
This study tests how well the meningitis B vaccine works in transgender and cisgender people. It aims to understand if sex and gender affect immune responses.
GhentAges 18–50 - NCT06876467Recruiting
Study of immune response to hepatitis B vaccine
This study looks at how your body's cells respond after getting a hepatitis B vaccine. It may help researchers understand how well the vaccine works.
ParisAges 18 years+ - NCT06262776Recruiting
Shingles vaccine safety study for transplant recipients
This trial tests whether the shingles vaccine (RZV) is safe and works well for organ transplant recipients and their household members. It also includes people on dialysis or certain immunosuppressants.
Adelaide, South AustraliaAges 18 years+ - NCT05923970Recruiting
MMRV vaccine booster in pregnant adults in Alberta
This study looks at whether getting a third dose of the MMRV vaccine during pregnancy is helpful. It focuses on pregnant women who were screened for rubella immunity during routine prenatal testing.
Edmonton, AlbertaAges 18 years+ - NCT06128915RecruitingPhase 4
Study of age and immune response to pneumococcal vaccine
This study is looking at how age affects the immune system's response to a pneumococcal vaccine. Researchers want to compare younger and older adults to see if immune cells change with age.
Buffalo, New YorkAges 21 years+ - NCT06907667Recruiting
Do timing of flu shot affect protection in kidney failure?
This study looks at whether getting a flu shot at a different time of day affects how well it works in people with chronic kidney failure, including those on dialysis or with a kidney transplant. Researchers want to see if timing can improve the body's immune response to the vaccine.
Nice, Alpes-MaritimesAges 18–100 - NCT07626606Recruiting
Gut Health and Rotavirus Vaccine Response in Adults
This study examines how the health of your digestive system affects how well your body responds to an oral rotavirus vaccine (a vaccine given by mouth to protect against rotavirus infection). You'll have two endoscopy procedures—a camera test to look inside your digestive tract—and provide samples to help researchers understand this connection.
Lusaka, Lusaka ProvinceAges 18–50 - NCT07636044Recruiting
Shingles Vaccine Response in Lupus Patients
This study tests how well the shingles vaccine (Shingrix) works in people with lupus who take immune-suppressing medications. Researchers want to understand if the vaccine provides good protection in lupus patients, since their immune systems work differently.
SeoulAges 50 years+ - NCT03875703Recruiting
Biology sample collection after routine vaccination
This study collects biological samples (like blood and/or other samples) after you get a routine vaccine. It helps researchers learn more about how vaccines affect the body.
CréteilAges 18 years+ - NCT06336317RecruitingPhase 4
Flu vaccine after heart attack: effect on heart inflammation
This trial tests whether getting a flu vaccine shortly after a heart attack can reduce inflammation in the heart. If you've recently had a non-ST-segment elevation heart attack and a stent placed, you may be able to join.
AarhusAges 18 years+ - NCT07047053Recruiting
Shingles vaccine study for people with autoimmune diseases
This study looks at how well the shingles vaccine works in people with autoimmune inflammatory diseases. Researchers want to make sure the vaccine provides good protection for patients whose immune systems are affected by their condition or treatment.
ParisAges 18 years+ - NCT03705585RecruitingPhase 4
Check how typhoid and cholera vaccines work in adults
This study gives (or follows) typhoid and/or cholera vaccines and measures how your immune system responds. It is done in adults who are already scheduled for an upper endoscopy (EGD) and/or colonoscopy, using small tissue samples if appropriate.
Baltimore, MarylandAges 18 years+ - NCT03501576Recruiting
Testing a flu or COVID vaccine response in people with lymphoma
This study checks how your immune system responds after getting a vaccine. It focuses on people with different types of lymphoma, aiming to learn which immune responses can be measured and whether the vaccines are safe for you.
Atlanta, GeorgiaAges 18 years+ - NCT06463119Recruiting
Vaccine response registry for immune-weakened patients
This study creates a registry to track how people with weakened immune systems respond to vaccines. It helps doctors better understand which vaccines work best for patients like you.
GenevaAges Any age - NCT05170399RecruitingPhase 4
Testing how cancer vaccines work in B-cell blood cancers
This study measures how well certain vaccines stimulate the immune system in people with B-cell blood cancers such as CLL and different types of lymphoma or Waldenström macroglobulinemia. It may help doctors better predict who will benefit most from vaccination and improve vaccine planning for these conditions.
Bethesda, MarylandAges 18–90 - NCT05291676RecruitingPhase 2
Study how vaccines work in aging and frailty adults
This trial studies how well your immune system responds to a vaccine in people who are younger adults or, especially, older adults and those with frailty. Your participation may help researchers understand why vaccine responses can differ with age.
New Haven, ConnecticutAges 21 years+ - NCT06784167Recruiting
Vaccine response after CAR-T for myeloma and lymphoma
This study looks at how well vaccines work in people with multiple myeloma or certain lymphomas after they receive CAR-T cell therapy. It aims to help doctors understand the best way to revaccinate patients to protect against preventable diseases.
Portland, OregonAges 18 years+ - NCT04948619RecruitingPhase 2
Vaccine response after cancer therapy in kids
This study is checking how well the immune system works and responds to vaccines in children and young adults who have recently finished cancer treatment. It may help doctors understand if vaccines are safe and effective after therapy.
Charlotte, North CarolinaAges 2–21 - NCT04871932Recruiting
Study of immune response to a COVID-19 vaccine
This trial studies how your immune system responds after a COVID-19 vaccine. It uses detailed blood tests to understand what changes happen in your immune cells and may help researchers improve future vaccines.
ShanghaiAges 18–50
Hear when a new Vaccine Response trial opens
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Common questions
- Are there clinical trials for vaccine response?
- Yes. Clin2 currently lists 62 recruiting vaccine response studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vaccine response trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vaccine response trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.