Clinical trials
Von Willebrand Disease (VWD) clinical trials
Below are recruiting von willebrand disease (vwd) clinical trials, each written for real people, not researchers. We’re tracking 18 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07575308RecruitingPhase 2
ALN-6400 for Heavy Bleeding in von Willebrand Disease
This trial tests a new medicine called ALN-6400 in teenage and adult women with von Willebrand disease (a blood clotting condition) who experience heavy menstrual bleeding. The goal is to see if this treatment can reduce bleeding and improve quality of life.
Los Angeles, CaliforniaAges 16–45 - NCT04146376Recruiting
Study of medicines for Von Willebrand disease during pregnancy
This study looks at how well a Von Willebrand disease treatment plan works during pregnancy, and whether some patients need extra “adjusting” of medicine. It may help prevent bleeding problems by matching treatment to each person’s lab results later in pregnancy.
Aurora, ColoradoAges 18 years+ - NCT05437536Recruiting
Severe von Willebrand disease patient registry in the U.S.
This registry collects health and bleeding information from people who have severe von Willebrand disease (a lifelong bleeding condition). Your data helps researchers understand the condition better and supports future studies that may lead to better treatments.
Wellington, FloridaAges Any age - NCT05500807RecruitingPhase 1
Emicizumab study for severe von Willebrand disease or overlap disorder
This Phase 1 trial studies how well and safely emicizumab works for people with severe von Willebrand disease (VWD) or VWD plus hemophilia A. Emicizumab is a preventive medicine given regularly to reduce bleeding risk.
Orange, CaliforniaAges birth–90 years - NCT05582993RecruitingPhase 3
Study of rVWF for severe bleeding disorder in children
This Phase 3 trial tests vonicog alfa (an rVWF treatment) to prevent and control bleeding in children with severe von Willebrand disease (vWD). You may be able to join if your child has severe vWD and has been on prior clotting factor treatment with ongoing bleeding despite that care.
Birmingham, AlabamaAges Up to 17 years - NCT05776069RecruitingPhase 1/Phase 2
Test drug VGA039 for bleeding control in von Willebrand disease
This Phase 1/2 study tests VGA039 in healthy adults and people with von Willebrand disease (VWD). The goal is to see if the drug is safe and how it affects bleeding-related factors, especially in people who have symptoms.
Los Angeles, CaliforniaAges 12–60 - NCT06205095RecruitingPhase 3
Wilate for heavy menstrual bleeding in von Willebrand disease
This trial tests whether a medicine called Wilate, given regularly (prophylaxis), can reduce heavy menstrual bleeding in women with von Willebrand disease. It compares Wilate to a placebo (a dummy treatment) to see if it helps more than no treatment.
Toronto, OntarioAges 18 years+ - NCT06998524RecruitingPhase 3
Testing emicizumab for type 3 von Willebrand disease
This study tests whether emicizumab can help prevent or treat bleeding episodes in people with type 3 von Willebrand disease, a rare and severe bleeding disorder. It may offer a new option for those who have not had good control with standard treatments.
Sacramento, CaliforniaAges 1 month+ - NCT06610201Recruiting
Study of a new treatment for Von Willebrand disease bleeding
This study is testing a new treatment for people with certain types of Von Willebrand disease (Type 1 or 2A) who have frequent bleeding problems. It aims to see if the treatment can help reduce these bleeding episodes.
Phoenix, ArizonaAges 16 years+ - NCT06651255Recruiting
Algorithm-guided care for bleeding in Von Willebrand disease
This trial tests whether a special algorithm can reduce repeat bleeding from the gut or nose in people with inherited Von Willebrand disease. If you have had serious nosebleeds or digestive bleeding, this study may help find a better way to manage your condition.
Lille, NordAges 18 years+ - NCT07115004RecruitingPhase 3
Testing an injectable drug for von Willebrand disease
This trial tests a new drug called VGA039 that is injected under the skin to prevent bleeding episodes in people with von Willebrand disease. It is for those who bleed frequently and are not currently using regular preventive treatments.
Little Rock, ArkansasAges 12–75 - NCT07129343RecruitingPhase 3
Study of a new VWF treatment for von Willebrand disease in China
This Phase 3 trial tests an recombinant version of the von Willebrand factor (rVWF) for people with severe von Willebrand disease (VWD) living in China. It aims to see if the drug can safely control bleeding and help those who need regular clotting factor treatments.
BeijingAges 18 years+ - NCT07273721RecruitingPhase 2
Testing BT200 in type 2B von Willebrand disease
This trial tests a new medicine called BT200 (rondaptivon pegol) to see if it can safely help people with type 2B von Willebrand disease who have low platelets and recent bleeding problems.
Vienna, State of ViennaAges 18 years+ - NCT07358013Recruiting
Endothelial cells in von Willebrand disease and related conditions
This study looks at special cells from blood vessels (endothelial colony-forming cells) in people with von Willebrand disease (a bleeding disorder) or a related acquired condition. The goal is to better understand these conditions using blood donations.
MilanAges 16 years+ - NCT06754852RecruitingPhase 1/Phase 2
Study of HMB-002 for von Willebrand disease
This study tests a new medicine called HMB-002 for people with von Willebrand disease. It aims to see if the drug can help control bleeding without needing regular preventive treatments.
Phoenix, ArizonaAges 16–69 - NCT07404644Recruiting
Study of vonicog alfa in children with von Willebrand disease
This study looks at how well vonicog alfa (a lab-made version of a missing blood protein) works to control bleeding in children under 18 with von Willebrand disease. It follows children who are already prescribed this treatment in Japan to see how safe and effective it is in real life.
Tokyo, TokyoAges Up to 17 years - NCT07640893RecruitingPhase 2
Testing a new injection for von Willebrand disease
This study tests whether SR604, a new injection given under the skin, can reduce bleeding episodes in people with von Willebrand disease (a condition where blood doesn't clot properly). The trial will measure how well it works, how safe it is, and how your body processes it.
ChangshaAges 18–65 - NCT04398628Recruiting
Study of non-cancer blood disorders in people with bleeding or clotting
This study follows people with inherited or acquired non-cancer blood disorders to better understand symptoms, causes, and how different treatments work over time. You may be placed into a disorder-specific group, depending on your diagnosis and testing results.
Phoenix, ArizonaAges Any age
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Von Willebrand Disease (VWD) trials by city
Studies with a site in or near these metro areas.
Von Willebrand Disease (VWD) trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for von willebrand disease (vwd)?
- Yes. Clin2 currently lists 18 recruiting von willebrand disease (vwd) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a von willebrand disease (vwd) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a von willebrand disease (vwd) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.