Clinical trials · California
Weight Loss clinical trials in California
We’re tracking 13 recruiting weight loss studies with a site in California — including Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07015424Recruiting
TORe procedure vs lifestyle changes for weight regain after bypass
This study compares a procedure called TORe (a way to reduce the size of your stomach opening) combined with lifestyle changes versus lifestyle changes alone to help people who have regained weight after gastric bypass surgery. The goal is to see which approach works better for long-term weight control.
Irvine, CaliforniaAges 18 years+ - NCT07503210RecruitingPhase 3
Study of a new medicine to maintain weight loss
This study tests an investigational medicine to help people who have lost weight keep it off. It's for adults without diabetes who haven't used similar weight-loss drugs before.
Walnut Creek, CaliforniaAges 18 years+ - NCT07419854RecruitingPhase 4
Restoring facial fullness after GLP-1 weight loss with Radiesse
This trial tests whether a facial filler called Radiesse can restore volume lost during weight loss from GLP-1 medications (like Wegovy or Mounjaro). It's for adults just starting GLP-1 therapy who expect to lose 20 pounds or more and want to see if fillers can help their face look fuller.
Pasadena, CaliforniaAges 21–65 - NCT03123835Enrolling by invitation
Testing POEM and other procedures for reflux and swallowing problems
This trial studies how well POEM and other endoscopy-based (through-the mouth) treatments work for conditions like acid reflux, achalasia (trouble moving food), and Barrett’s esophagus. It may help doctors compare outcomes and choose the safest, most effective procedure for your situation.
Sacramento, CaliforniaAges 18–80 - NCT07770841RecruitingPhase 3
Oral medication for weight loss study
This study tests an oral medicine (semaglutide) to see if it helps adults with excess weight lose weight. It might offer an easier, pill-based treatment option for weight management.
Escondido, CaliforniaAges 18 years+ - NCT04453072Recruiting
iPhone weight-loss app for teens and young adults after transplant
This study tests whether an iPhone weight-management app can help adolescents and young adults lose weight after a stem cell transplant. If you qualify, you’ll use the app and the team will track changes in weight.
Los Angeles, CaliforniaAges 13–30 - NCT06937177RecruitingPhase 2
Testing mifomelatide to help maintain weight during chemo
This trial tests an investigational drug called mifomelatide (TCMCB07) to see if it can help people with newly diagnosed colorectal or pancreatic cancer maintain a healthy weight while receiving certain types of chemotherapy. You would give yourself a daily injection under the skin.
Los Angeles, CaliforniaAges 18 years+ - NCT06989437RecruitingPhase 2/Phase 3
Study of Ponsegromab for Pancreatic Cancer with Weight Loss
This study tests an experimental drug called ponsegromab for people with advanced pancreatic cancer who experience severe weight loss and fatigue. It aims to see if the drug can help improve weight and energy levels while you continue standard chemotherapy.
Encinitas, CaliforniaAges 18 years+ - NCT03824652RecruitingPhase 2
Walnuts and omega-3 to help weight loss before prostate surgery
This Phase 2 study tests whether adding walnuts (and related nutrients like omega-3s) can help with weight loss and energy in people with prostate cancer who are planning prostate removal surgery. It aims to see if diet changes improve how you feel and manage weight before and around treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT06988150Recruiting
SIBO and weight loss in pancreatic cancer
This study looks at whether a condition called SIBO (too many bacteria in the small intestine) is linked to weight loss in people with pancreatic cancer. You might join if you have pancreatic cancer and have lost weight recently.
Los Angeles, CaliforniaAges 18 years+ - NCT04721873RecruitingPhase 2
Weight-loss medicine for people with ulcerative colitis
This study tests whether a weight-loss medication, along with usual ulcerative colitis care, can help people who have both ulcerative colitis and obesity. It focuses on people with active symptoms or who need ongoing steroid medicine, and it also checks safety with heart, blood, infection, and mental-health screenings.
La Jolla, CaliforniaAges 18–80 - NCT04997473Recruiting
Mobile app weight-loss program for young transplant patients
This trial tests whether a phone app can help young people who previously had a stem cell transplant lose weight. It’s designed for people who are at least 100 days out from transplant and who meet weight criteria.
Los Angeles, CaliforniaAges 13–30 - NCT05530538Recruiting
Phone app program to help teens manage weight
This study tests a weight-management app (the BrainWeighve app) for teens. It looks at whether the app is workable and helpful for teens who are motivated to change weight habits.
Los Angeles, CaliforniaAges 14–21
Weight Loss trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting weight loss studies listed above.
- Cedars-Sinai Medical Center · 4 studies
- University of California San Diego Health · 2 studies
- University of California, Los Angeles (UCLA) · 2 studies
- Diablo Clinical Research
- Headlands Research - AMCR Institute
- Hoag Memorial Hospital Presbyterian
- K. Kay Durairaj, MD, A Medical Corp.
- Los Angeles Institute for Metabolic Research
What taking part in a weight loss study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Weight Loss trials in other states
Common questions
- Are there weight loss clinical trials in California?
- Yes. We're currently tracking 13 recruiting weight loss studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a weight loss study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a weight loss trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New weight loss studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.