Clinical trials · North Carolina
Weight Loss clinical trials in North Carolina
We’re tracking 10 recruiting weight loss studies with a site in North Carolina — including Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in North Carolina
- NCT06428617Recruiting
Stomach ablation treatment for weight loss
This trial studies a new stomach procedure called fundus ablation to help with weight loss. The doctor uses a device to treat the upper part of your stomach, and you'll follow a special diet long-term.
Cary, North CarolinaAges 18–65 - NCT06420700Recruiting
Stomach Lining Ablation with Sleeve Gastroplasty for Weight Loss
This study combines two endoscopic procedures to help you lose weight: one that reduces the size of your stomach and one that alters the stomach lining. It is designed for people who are ready to commit to long-term diet changes.
Cary, North CarolinaAges 18–65 - NCT06724406Recruiting
Family-centered weight loss for Black adults
This trial tests a weight loss program for Black adults and a family partner. You and a family member work together to lose weight with support from a smartphone or computer.
Chapel Hill, North CarolinaAges 18–75 - NCT07503210RecruitingPhase 3
Study of a new medicine to maintain weight loss
This study tests an investigational medicine to help people who have lost weight keep it off. It's for adults without diabetes who haven't used similar weight-loss drugs before.
Greensboro, North CarolinaAges 18 years+ - NCT07446998RecruitingPhase 2
Study on enobosarm for weight loss in older adults on semaglutide
This trial tests if adding enobosarm (a muscle-preserving drug) to semaglutide (a weight-loss medication) can help older adults maintain muscle and improve physical function while losing weight. It may be an option for people who are already taking semaglutide and want to prevent muscle loss.
Fayetteville, North CarolinaAges 65–100 - NCT06937177RecruitingPhase 2
Testing mifomelatide to help maintain weight during chemo
This trial tests an investigational drug called mifomelatide (TCMCB07) to see if it can help people with newly diagnosed colorectal or pancreatic cancer maintain a healthy weight while receiving certain types of chemotherapy. You would give yourself a daily injection under the skin.
Durham, North CarolinaAges 18 years+ - NCT06989437RecruitingPhase 2/Phase 3
Study of Ponsegromab for Pancreatic Cancer with Weight Loss
This study tests an experimental drug called ponsegromab for people with advanced pancreatic cancer who experience severe weight loss and fatigue. It aims to see if the drug can help improve weight and energy levels while you continue standard chemotherapy.
Chapel Hill, North CarolinaAges 18 years+ - NCT06658912Recruiting
Weight loss program for breast cancer survivors
This study tests a weight loss program designed specifically for women who have finished breast cancer treatment. It aims to help improve overall health after cancer.
Durham, North CarolinaAges 21–90 - NCT04320264Recruiting
Study tests muscle fuel patterns in adults with BMI 25–30
This study looks at how your muscles use fuel during exercise by measuring blood lactate. It may help researchers understand “metabolic inflexibility” and why some people rely more on fast, short-lasting energy during activity.
Greenville, North CarolinaAges 18–50 - NCT06044571Recruiting
Weight loss program for older adults via telehealth
This trial tests a weight loss program delivered through video calls to help adults aged 65-85 with obesity lose weight. It is designed for those with at least two other health conditions and who are ready to make changes.
Chapel Hill, North CarolinaAges 65–85
Where these studies are running in North Carolina
Institutions with a site for the recruiting weight loss studies listed above.
- True You Weight Loss · 2 studies
- University of North Carolina at Chapel Hill · 2 studies
- Coastal Research Institute
- Duke University
- Duke University Medical Center
- East Carolina University
- Levine Cancer Institute
- Medication Management
What taking part in a weight loss study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Weight Loss trials in other states
Common questions
- Are there weight loss clinical trials in North Carolina?
- Yes. We're currently tracking 10 recruiting weight loss studies with a site in North Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a weight loss study in North Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in North Carolina to take part?
- Not necessarily. These studies have a site in North Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a weight loss trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New weight loss studies open in North Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.