Clin2
NCT04721873Possibly a fitRecruiting

Weight-loss medicine for people with ulcerative colitis

Colitis, UlcerativeObesity

Part of Digestive system, Hormones & metabolism clinical trials.

This study tests whether a weight-loss medication, along with usual ulcerative colitis care, can help people who have both ulcerative colitis and obesity. It focuses on people with active symptoms or who need ongoing steroid medicine, and it also checks safety with heart, blood, infection, and mental-health screenings.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
40 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You’re an adult age 18–80.
  • Your body mass index (BMI) is 30 or higher.
  • You have a confirmed diagnosis of ulcerative colitis (UC) and it is currently active, or you depend on prednisone/steroids (can’t taper below 10 mg or you flare when stopping).
  • You will start a new biologic UC medicine or you are flaring even though your current biologic dose has been stable.
  • Your weight has been fairly steady for at least 4 weeks (less than 5 kg change).
  • You must be able to speak/understand English and sign written consent.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07731139Not yet recruiting· Phase 1
Testing a new medicine for people with obesity

This study tests how different amounts of the study medicine PF-08642534 are tolerated and how they work in the body of people with obesity. It aims to find a safe dose for future studies.

Lake Forest, California
NCT06143956Recruiting· Phase 2
Weight loss treatments for adults with obesity

This clinical trial tests new treatments for adults who are overweight or have obesity. The goal is to help people lose weight and improve their health.

Chandler, Arizona
NCT07507929Not yet recruiting
Probiotics for weight loss in overweight adults

This trial tests whether a probiotic supplement can help overweight or obese adults lose weight when combined with a low-carb, reduced-calorie diet. It may be a good option if you are looking for extra support alongside dietary changes.

Luoyang, Henan
NCT07467447Recruiting· Phase 2
Testing a weight-loss drug for people with obesity or overweight

This trial tests whether an experimental drug (LY3437943) can help people with obesity or overweight lose weight. It compares the drug to a placebo (inactive shot), and you must be willing to give yourself daily injections.

Shenzhen, Guangdong
NCT07437079Recruiting· Phase 1
Testing a new weight-loss medicine in healthy people

This study tests a new medicine (NNC6989-0001) for people who are overweight or have obesity. It checks if the medicine is safe and how the body handles it. If eligible, you would receive the study drug and be monitored closely.

Lenexa, Kansas
NCT07339423Recruiting· Phase 3
A study of a new medicine for weight loss

This study tests a new medicine to see how well it helps people with excess body weight lose weight. It may be an option if you have tried to lose weight through dieting before but haven't had lasting success.

Miramar, Florida

Hear when a new Obesity trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.