Clinical trials
White Spot Lesions clinical trials
Below are recruiting white spot lesions clinical trials, each written for real people, not researchers. We’re tracking 15 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07664046Recruiting
Peptide for remineralizing white spot lesions in teens
This trial tests a self-assembling peptide (P11-4) to help reverse early white spots on teeth caused by cavities in teenagers. If effective, it could rebuild enamel without drilling or fillings.
Warsaw, Masovian VoivodeshipAges 10–18 - NCT07146464Recruiting
Peptide vs calcium paste for early cavity spots
This trial tests whether a new peptide treatment or a calcium-phosphate paste works better at reversing early white-spot cavities on front teeth. If you're a young adult with early decay on your front teeth, you may be able to join.
Cairo, Cairo GovernorateAges 15–25 - NCT07325643Recruiting
Toothpaste and mouthwash to prevent white spots during braces
This study tests if a special toothpaste and mouthwash can stop white spots from forming on teeth while you have braces. It is for people starting orthodontic treatment who have healthy teeth and gums.
BaghdadAges Any age - NCT07289932Enrolling by invitation
Peptide vs fluoride varnish for white spots on teeth
This study compares a new peptide treatment to a standard fluoride varnish for reversing small white spots on teeth (early cavities) in teens and young adults. You’ll receive one treatment on one side of your mouth and the other treatment on the other side, and we’ll see which works better.
CairoAges 15–25 - NCT06708481RecruitingEarly Phase 1
Resin vs peptide gel for white spots on teeth in children
This study compares two treatments for white spots on teeth: a resin (tooth-colored coating) and a special peptide gel that helps rebuild enamel. It is for children and young teens with early white spots that haven't been treated yet.
Cairo, Giza GovernorateAges 7–14 - NCT07730359Recruiting
Testing a treatment for white spots after braces
This trial tests a new gel called Epinamel to reverse white spots that form on teeth after braces are removed. If you recently had braces taken off and have white marks on your teeth, this study might help improve them.
LondonAges 12–60 - NCT05733676Recruiting
MI Paste Plus vs resin for white spots after braces
This trial compares two tooth treatments to see which one works better for “white spot” areas that can appear after braces come off. If you have mild plaque buildup and at least one white spot on front teeth, you may be eligible to test one of these options and improve tooth surface healing.
Edmonton, AlbertaAges 12–21 - NCT07247760Enrolling by invitation
Whitening for white spots on teeth
This trial tests a home whitening gel (10% carbamide peroxide) to see if it can make white spots on front teeth less noticeable and if people are happy with the results. It might help if you have white spots and want a simple way to improve your smile.
Alcorcón, MadridAges 18 years+ - NCT06489093RecruitingEarly Phase 1
Silver agents for early cavities in children's baby teeth
This study checks if silver-containing agents can help heal early white spots (cavities) on baby teeth of children aged 3 to 8. It compares different silver treatments to see which works best for stopping or reversing these early cavities.
PlovdivAges 3–8 - NCT06824493Recruiting
How Braces Affect Mouth Bacteria and Saliva
This study looks at how braces (orthodontic treatment) change the bacteria and proteins in your mouth. Healthy volunteers who have never had dental work or cavities are needed to provide saliva samples before and during treatment.
Xi'an, ShaanxiAges 6–18 - NCT07091422Recruiting
Testing a new brace glue: does it hold better?
This trial tests a new no-etching glue for braces. Half of your mouth will get the new glue, the other half a standard glue, to see which one holds the brackets better over a year.
Baltimore, MarylandAges 14–35 - NCT07111403Recruiting
Testing remineralizing agents for early white spots on teeth
This study tests whether a special remineralizing agent can help reverse early white spots (soft spots) on adult teeth before they become cavities. It's for people who have a few small spots but keep their teeth clean.
Al MansurahAges 14–26 - NCT05989750Recruiting
Air-Polishing Teeth Cleaner During Braces Treatment
This study tests a special air-polishing cleaning method using erythritol (a gentle powder) during braces treatment. It may help keep teeth and gums healthier while you have braces.
Geneva, Canton of GenevaAges 12–16 - NCT06172764RecruitingPhase 4
Vitamin D for early cavities: a saliva study
This study tests whether vitamin D supplements can help improve the health of your mouth by looking at changes in saliva and the bacteria that cause cavities. If you have early cavities and low vitamin D, you may be able to join.
Karachi, SindhAges 12–50 - NCT07244991Recruiting
Effect of a special toothpaste on plaque bacteria and cavities during braces treatment
This trial tests whether a special paste (MI Paste Plus) can reduce cavity-causing bacteria and prevent early white spots on teeth while you are wearing braces.
Tirana, AlbaniaAges 5–45
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Common questions
- Are there clinical trials for white spot lesions?
- Yes. Clin2 currently lists 15 recruiting white spot lesions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a white spot lesions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a white spot lesions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.