Clinical trials
HSIL, High Grade Squamous Intraepithelial Lesions clinical trials
Below are recruiting hsil, high grade squamous intraepithelial lesions clinical trials, each written for real people, not researchers. We’re tracking 12 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06626230RecruitingPhase 1
Safety of curcumin for anal precancer
This study tests whether a curcumin (turmeric) suppository can safely treat anal precancerous changes called AIN 2 or AIN 3. It may be an option if you have high-grade cell changes and want to avoid more invasive treatments.
Atlanta, GeorgiaAges 30 years+ - NCT06206564RecruitingPhase 2
Artesunate ointment for anal precancer in HIV-negative adults
This trial tests an artesunate ointment to treat high-grade anal precancer (HSIL) in people who do not have HIV. The goal is to see if the ointment can clear the abnormal cells caused by HPV.
Chicago, IllinoisAges 18 years+ - NCT06356012RecruitingPhase 4
Imiquimod for high-risk HPV cervical lesions
This trial tests if imiquimod cream can help clear high-grade cervical lesions caused by high-risk HPV. It may be an option for people who want to avoid surgery.
BarretosAges 25–45 - NCT07047989RecruitingPhase 1
NWRD09 for HPV-16 related cervical high-grade changes
This trial tests a new drug called NWRD09 for women with high-grade cervical cell changes (CIN 2/3) caused by HPV type 16. The goal is to see if the drug can help clear these abnormal cells without needing surgery.
BeijingAges 18–65 - NCT07175662RecruitingPhase 2
A new treatment for HPV-related high-grade cervical changes
This study tests a new treatment (NWRD08) for women with high-grade cervical changes (CIN 2/3) caused by HPV types 16 or 18. It aims to see if the treatment can help clear the abnormal cells and prevent them from becoming cancer.
Beijing, Beijing MunicipalityAges 18–60 - NCT05282095Recruiting
Study how HPV changes affect outcomes in CIN2
This study follows women with an early abnormal cervix cell change (CIN2/CIN2-3) to see how HPV DNA “integration” relates to whether the condition improves or worsens. It may help doctors better predict prognosis and guide safer monitoring, especially if you want to become pregnant.
Fuzhou, FujianAges Up to 45 years - NCT05405270Recruiting
Testing how well imiquimod works for abnormal cervix cell changes
This study looks for ways to predict who will respond to imiquimod cream for precancerous cervical cell changes (CIN2 or CIN3). Results may help doctors choose the best treatment approach and better plan follow-up.
BredaAges 18 years+ - NCT06075264RecruitingPhase 2
Artesunate ointment for high-grade vulvar lesions
This trial tests an artesunate ointment for women with high-grade vulvar lesions caused by HPV. It aims to see if the ointment can help the lesions heal or disappear without needing surgery.
Fort Myers, FloridaAges 18 years+ - NCT07029152Recruiting
Anal cancer screening for gay and bisexual men on PrEP
This study is screening gay and bisexual men for anal cancer by taking a swab sample. It aims to find early signs of cancer so it can be treated early.
BrugesAges 35 years+ - NCT07480902Recruiting
Comparing two tests for cervical cancer detection
This trial compares a liquid-based cytology test with a molecular screening test to find early changes in the cervix that could lead to cancer. It may help you understand which test is better at detecting these changes before they become serious.
Mexico City, Mexico CityAges 18–85 - NCT07572396RecruitingPhase 2
HPV treatment with vaginal suppositories for mild cervical changes
This study tests a new vaginal medication (Dysplasix) to treat mild cervical cell changes caused by high-risk HPV. The goal is to see if this treatment can help your body clear the virus and prevent these changes from getting worse.
Shatin, New TerritoriesAges 18–65 - NCT06982976Recruiting
Light therapy for abnormal cervical or vaginal cells
This trial tests a light-based treatment (photodynamic therapy) for high-grade or persistent low-grade abnormal cells in the cervix or vagina. It aims to destroy these cells without surgery, which may be an option for patients who want to avoid more invasive procedures.
Beijing, Beijing MunicipalityAges 18–65
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Common questions
- Are there clinical trials for hsil, high grade squamous intraepithelial lesions?
- Yes. Clin2 currently lists 12 recruiting hsil, high grade squamous intraepithelial lesions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hsil, high grade squamous intraepithelial lesions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hsil, high grade squamous intraepithelial lesions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.