Treatment
Cohort 2 clinical trials
We’re tracking 50 recruiting studies that include Cohort 2, each written for real people, not researchers, below.
Recruiting studies
- NCT07263438RecruitingPhase 2
Trimipramine, atezolizumab, and bevacizumab for recurrent glioblastoma
This trial tests a combination of three drugs—trimipramine (an antidepressant), atezolizumab (an immunotherapy), and bevacizumab (a targeted therapy)—in people whose glioblastoma has come back after initial treatment. The goal is to see if this mix can help shrink the tumor or slow its growth.
Basel, BaselAges 18 years+ - NCT07753343Recruiting
Study of high-risk kidney cancer patients
This study looks at patients with kidney cancer that hasn't spread and is considered high-risk. It uses a registry to learn more about these patients to improve future care.
BordeauxAges 18 years+ - NCT06327295RecruitingPhase 2
Testing a new treatment for mild to moderate toenail fungus
This trial tests an investigational medication called ATB1651 for people with toenail fungus (onychomycosis). If you have a fungal infection covering 20% to 60% of one or both big toenails and are in generally good health, you may be able to join.
ChristchurchAges 18–70 - NCT06417762Recruiting
A study testing social media health messages for community health workers
This trial teaches community health workers how to find and share true health information on social media, and how to spot and stop false information. It aims to reduce illness from respiratory viruses in seven communities.
Chicago, IllinoisAges 18–99 - NCT07488546Enrolling by invitationPhase 1/Phase 2
HCL001 cell therapy for advanced liver cirrhosis
This trial tests a new cell injection called HCL001 for people with decompensated cirrhosis (advanced liver scarring causing complications). The goal is to see if it's safe and helps improve liver function. It may be an option if you've tried standard treatments and meet specific health criteria.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06891885RecruitingPhase 1/Phase 2
Safety study of DSP-3077 for retinitis pigmentosa
This trial tests a new medicine, DSP-3077, given as a single injection into one eye to see if it is safe for people with retinitis pigmentosa. It is for adults with advanced vision loss who have no other major eye diseases.
Boston, MassachusettsAges 18 years+ - NCT07612878Recruiting
Registry tracking COPD patients starting dupilumab treatment
This is a registry—an observational study tracking patients with COPD (chronic lung disease) who are newly starting a medication called dupilumab. Researchers will follow your health outcomes to learn how well this treatment works in real-world practice.
Indianapolis, IndianaAges 40 years+ - NCT04199741RecruitingPhase 1/Phase 2
PET/CT scan test for small cell lung cancer marker DLL3
This trial tests a special PET/CT imaging scan that may help doctors find where small cell lung cancer (and some related tumors) are in the body using a DLL3 target. It’s a Phase 1/2 study, mainly to see how well the scan detects tumors and guides care.
New York, New YorkAges 18 years+ - NCT07283367RecruitingPhase 1/Phase 2
New drug combo for advanced colorectal cancer
This trial tests a new combination of targeted therapies for people with advanced colorectal cancer that has a certain genetic pattern (non-MSI-H, no BRAF V600E mutation). It aims to see if the combination can shrink tumors or slow the cancer's growth.
GuangzhouAges 18 years+ - NCT06185673RecruitingPhase 1/Phase 2
Gene therapy trial for OPMD with swallowing problems
This trial tests an experimental gene therapy (BB-301) for people with OPMD who have trouble swallowing. It involves a one-time injection into the throat muscles during a short surgery, and researchers will check if it is safe and improves swallowing.
New York, New YorkAges Up to 65 years - NCT07072221Recruiting
Matching drugs trial for relapsed T-cell lymphoma
This trial tests a combination of three drugs (bendamustine, chidamide, and lenalidomide) for patients with peripheral T-cell lymphoma that has come back or not responded to treatment. It aims to see if this new combination can help when standard treatments have failed.
Suzhou, JiangsuAges 18 years+ - NCT06145308RecruitingPhase 2
Precision treatment for salivary gland cancer
This trial tests a personalized treatment approach for recurrent or metastatic salivary gland cancer. It uses special tests on your tumor to find the best targeted therapy for your specific cancer type.
Beijing, Beijing MunicipalityAges 18–100 - NCT07772895RecruitingPhase 1
Glowing dye to help surgeons see lung cancer during surgery
This trial tests a dye that makes lung cancer cells glow during surgery, helping surgeons remove more of the tumor. It's for people who are already scheduled for lung cancer surgery.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06526923RecruitingPhase 1/Phase 2
Testing SP-101 gene therapy for cystic fibrosis
This trial tests a new gene therapy called SP-101 for cystic fibrosis. It aims to see if SP-101 is safe and effective for improving lung function.
Kansas City, KansasAges 18–65 - NCT05772559Recruiting
Study of AML genes and drug response in young patients
This trial looks at how childhood, teen, and young adult acute myeloid leukemia (AML) changes at the genetic level and how cells respond to multiple drugs. It may help doctors understand which treatments work best and how leukemia interacts with supportive cells in the bone marrow.
AmiensAges Up to 25 years - NCT02818192Recruiting
Kid-focused study to track kidney issues in type 2 diabetes
This study follows young people with type 2 diabetes to better understand risks for kidney problems over time. It may help researchers find earlier warning signs and improve care for adolescents living with type 2 diabetes.
Winnipeg, ManitobaAges 10–18 - NCT06769633RecruitingPhase 2
Study of givinostat in young boys with Duchenne muscular dystrophy
This trial tests an experimental drug called givinostat in boys ages 2 to under 6 years with Duchenne muscular dystrophy (DMD). The study looks at how the drug works in the body and if it is safe, with the goal of finding new treatment options for young children.
BrusselsAges 2–6 - NCT05253495RecruitingPhase 2
Targeted immunotherapy added to chemotherapy and radiation for lymphoma
This Phase 2 trial tests whether adding targeted immunotherapy to standard chemotherapy and radiation can improve outcomes in children with certain types of lymphoma. It may help the immune system work better against cancer.
Birmingham, AlabamaAges 3–39 - NCT07298369Recruiting
Cracking consciousness study with Monroe & Neuphoria
This study tests a new approach to understanding consciousness using digital tools. It might help you if you are curious about your own mind and willing to try new monitoring methods.
New York, New YorkAges 18 years+ - NCT06139458Recruiting
Cooling therapy to prevent nerve damage from chemo
This trial tests if cooling sleeves and gloves during chemotherapy can help prevent nerve damage (peripheral neuropathy) in people with gynecologic cancers. If you are receiving a common chemo drug called paclitaxel, this approach might reduce side effects like numbness or pain in your hands and feet.
Hartford, ConnecticutAges 18 years+ - NCT07606885Recruiting
Hangzhou Health and Lifestyle Study
This study collects detailed health information from people living in Hangzhou to understand how daily habits affect overall health. Researchers will ask questions and take samples to learn more about what keeps people healthy.
Hangzhou, ZhejiangAges 18–40 - NCT02583061Recruiting
Study of blood sugar changes during pregnancy
This study follows pregnant people to look at how blood sugar behaves during pregnancy. It may help doctors understand pregnancy-related blood sugar problems and who is at risk.
Toronto, OntarioAges 20–60 - NCT05697991Recruiting
Study of fatty liver in adults with type 2 diabetes
This study looks at people with type 2 diabetes who also have fatty liver. The goal is to learn more about this condition in a Saudi group and test approaches that could improve care.
Riyadh, Select A State Or ProvinceAges 18–60 - NCT06730113Recruiting
Young adults with type 2 diabetes and heart health study
This study looks at how type 2 diabetes starting in youth affects the heart over time. It also includes teens and young adults who are overweight or lean, and their biological parents, to compare heart health across these groups.
Washington D.C., District of ColumbiaAges 12–25
What Cohort 2 is being studied for
Conditions with recruiting Cohort 2 studies.
Common questions
- Are there clinical trials studying Cohort 2?
- Yes. Clin2 currently lists 50 recruiting studies that include Cohort 2, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Cohort 2 trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Cohort 2 an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Cohort 2 or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.