Treatment
Defibrotide clinical trials
We’re tracking 3 recruiting studies that include Defibrotide, each written for real people, not researchers, below.
Recruiting studies
- NCT02675959RecruitingPhase 2
Transplant with defibrotide for sickle cell disease
This trial tests a stem cell transplant from a half-matched donor using a strong conditioning regimen and a drug called defibrotide to protect organs. It aims to cure sickle cell disease in patients who have had serious complications like stroke, chest syndrome, or frequent pain episodes.
Los Angeles, CaliforniaAges 6 months–21 years - NCT04652115RecruitingPhase 2
Defibrotide for severe COVID-19 in adults
This trial tests defibrotide to see if it improves outcomes in people hospitalized with severe COVID-19. You may be considered if you have confirmed infection, abnormal chest imaging, and meet specific severity and safety requirements.
Boston, MassachusettsAges 18–100 - NCT05987124RecruitingPhase 2
Higher dose defibrotide for SOS after stem cell transplant
This study tests whether a higher dose of defibrotide can help patients who develop SOS/VOD after a stem cell transplant and haven't gotten better with the standard dose. SOS/VOD is a liver condition that sometimes also affects the kidneys or lungs.
Vallhala, New YorkAges 1 month–75 years
What Defibrotide is being studied for
Conditions with recruiting Defibrotide studies.
Common questions
- Are there clinical trials studying Defibrotide?
- Yes. Clin2 currently lists 3 recruiting studies that include Defibrotide, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Defibrotide trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Defibrotide an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Defibrotide or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.