Treatment
Local Anesthesia clinical trials
We’re tracking 67 recruiting studies that include Local Anesthesia, each written for real people, not researchers, below.
Recruiting studies
- NCT06960317Recruiting
Numbing injection for IUD placement pain
This study tests whether a numbing injection (lidocaine) in the cervix can reduce pain during IUD placement. It's for women who have never had a vaginal birth and are getting their first IUD.
La Jolla, CaliforniaAges 18–50 - NCT06986083RecruitingPhase 3
Testing changes in prostate biopsy and ablation care
This study looks at two ways to improve prostate procedures: 1) whether adding local anesthesia during a biopsy (while you’re already sedated) makes a difference, and 2) whether a standard care plan before and after focal gland ablation helps recovery compared to usual care.
Basking Ridge, New JerseyAges 18 years+ - NCT07060170Recruiting
Can VR or AR glasses help kids feel less pain at the dentist?
This study tests if wearing fun glasses that show virtual or augmented reality can help children feel less pain and worry when getting a numbing shot for a cavity. It compares two types of high-tech glasses to see which works better.
Cairo, EgyptAges 5–8 - NCT07130760Recruiting
Testing two numbing methods for tooth pain in a back molar
This trial compares two ways to numb a painful lower back molar. If you have a tooth infection that needs a root canal, you may receive one of two injection techniques to see which works better.
Ferrol, A coruñaAges 18 years+ - NCT07133919Recruiting
AI communication to reduce dental anxiety in children
This trial tests whether a child-friendly, AI-assisted conversation method can help reduce anxiety in children who need a dental filling, pulpotomy, or similar treatment. It is for children ages 6-12 who are coming to the dentist for the first time and will receive local anesthesia.
Çanakkale, KepezAges 7–12 - NCT07628660Recruiting
Sexual Function After Endometrial Sampling Procedure
This study asks women about their sexual function one month after a routine gynecologic procedure called endometrial sampling (a biopsy of the uterine lining). Researchers want to understand how this procedure affects sexual health when done with sedation or local numbing.
IstanbulAges 18–60 - NCT07638254Recruiting
Buffered vs. Standard Numbing for Dental Pain in Children
This study tests whether a specially prepared numbing medicine works better than standard numbing to reduce pain and anxiety during a dental procedure for children with a painful infected tooth. The goal is to find the gentlest way to numb the area before treatment.
San Luis Potosí City, San Luis PotosíAges 6–12 - NCT07499752Enrolling by invitation
Study on fewer tears: Local anesthesia for first vaginal birth
This study tests whether using local anesthesia during your first vaginal birth can reduce the risk of perineal tears. It aims to make childbirth safer and more comfortable.
StockholmAges 18–64 - NCT07371442Enrolling by invitation
Audio distraction and acupoint stimulation for kids during tooth extraction
This study tests two non-drug methods to help children feel less pain and worry during a tooth extraction: an audio-video distraction (like a movie or music) and a special pressure point (acupoint) stimulation on the hand. It aims to see which approach works best for kids ages 5 to 8 who need a baby tooth removed.
Al MansurahAges 5–8 - NCT06944314Enrolling by invitation
Doctors' views on pain during flexible cystoscopy with local anesthetic
This trial asks doctors to rate how much pain they think male patients feel during a minimally invasive bladder exam. It aims to see if doctors' estimates of pain are accurate.
Istanbul, IstanbulAges 18 years+ - NCT05230134Enrolling by invitation
Nerve block treatment for brain blood vessel spasm after bleeding
This trial looks at a procedure that blocks specific nerves to help prevent or treat blood vessel spasm in the brain after a ruptured brain aneurysm. If you qualify, it may help improve blood flow to the brain during recovery in the ICU.
Stanford, CaliforniaAges 18 years+ - NCT06041685Recruiting
Warming for artery catheter in children under 2
This trial tests if warming the skin before placing an artery line helps children having heart surgery. It may make the procedure easier and more comfortable.
Yangsan, Gyeongsangnam-doAges Up to 2 years - NCT04992572RecruitingEarly Phase 1
Comparing two types of anesthesia for back decompression surgery
This early study compares two anesthesia approaches during lumbar decompression (back surgery to relieve pressure on nerves). It may help improve comfort and safety during surgery, but whether you personally benefit is not yet known.
Redwood City, CaliforniaAges 40–95 - NCT06550869Recruiting
A new nerve block for less pain after kidney surgery
This trial tests a specific nerve block (anterior quadratus lumborum block) given during laparoscopic kidney surgery to see if it reduces pain and speeds recovery. It may help patients who need a nephrectomy (kidney removal) or partial nephrectomy.
Hangzhou, ZhejiangAges 18–80 - NCT05233462Recruiting
Compare two spinal anesthesia bupivacaine dose methods for C-sections
This trial looks at whether adjusting the dose of bupivacaine by height works better than using a standard dose for spinal anesthesia during planned C-sections. It may help improve safety and comfort by aiming for the right level of numbing effect.
CaenAges 18–45 - NCT06600945Recruiting
Comparing two muscle relaxants for cataract surgery
This trial tests if adding magnesium sulfate to a standard muscle relaxant (atracurium) improves local anesthesia for cataract surgery. It may help patients stay comfortable during the procedure.
MinyaAges 20–80 - NCT06617949RecruitingEarly Phase 1
Pain Control Study for New Mothers on Opioid Medication
This study looks at better ways to manage pain after childbirth for mothers who are taking medication for opioid use disorder. It aims to find which pain control method works best and is safest for you and your baby.
Milwaukee, WisconsinAges 18–40 - NCT05898581Recruiting
Compare two pain block methods for hip replacement surgery
This trial studies whether one type of numbing injection (a PENG block) works better than another method (local anesthetic injected into the surgical area) to control pain during and after total hip replacement. It may help choose the best pain plan for people having a specific surgical approach.
London, OntarioAges 19 years+ - NCT06600815Recruiting
Step-by-step numbing shots for pain relief in knee replacement
This study tests whether a special step-by-step numbing injection given before knee replacement surgery can provide better pain relief during and after the procedure. It may help you have less pain and use fewer painkillers after surgery.
Fuzhou, FujianAges 18 years+
Common questions
- Are there clinical trials studying Local Anesthesia?
- Yes. Clin2 currently lists 67 recruiting studies that include Local Anesthesia, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Local Anesthesia trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Local Anesthesia an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Local Anesthesia or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.