Treatment
Pregnenolone clinical trials
We’re tracking 5 recruiting studies that include Pregnenolone, each written for real people, not researchers, below.
Recruiting studies
- NCT07216690RecruitingPhase 2
Pregnenolone for cannabis intoxication treatment
This trial tests whether a natural steroid called pregnenolone can help treat symptoms of cannabis intoxication. If you qualify, you would receive either pregnenolone or a placebo after using cannabis to see how you feel.
Baltimore, MarylandAges 18–65 - NCT05781009RecruitingPhase 2
Pregnenolone treatment for alcohol use disorder
This Phase 2 study tests pregnenolone to help reduce or improve alcohol use disorder symptoms. It looks for adults who drink regularly and meet diagnostic criteria for moderate to severe alcohol use disorder, while excluding people with certain other substance use, medicines, or serious mental/medical conditions.
New Haven, ConnecticutAges 18–70 - NCT06238700Recruiting
Studying allopregnanolone for depression in midlife women
This trial tests whether allopregnanolone, a natural brain chemical, can help depression in women going through menopause. It compares the effects against a placebo to see if it improves mood symptoms.
Boston, MassachusettsAges 40–60 - NCT05570812RecruitingPhase 2
Pregnenolone to improve depressed mood in people with HIV
This Phase 2 trial tests a brain-acting steroid called pregnenolone to help reduce depressed mood. It studies whether it can improve mood in adults with HIV who are already on HIV treatment and still have depression symptoms.
Boston, MassachusettsAges 18–85 - NCT06188923RecruitingPhase 2
Pregnenolone for anxiety and depression in veterans
This trial tests whether a dietary supplement called pregnenolone can help veterans with anxiety and depression feel better and function better. It's a new approach that may be added to your current treatment.
Durham, North CarolinaAges 18–65
What Pregnenolone is being studied for
Conditions with recruiting Pregnenolone studies.
Common questions
- Are there clinical trials studying Pregnenolone?
- Yes. Clin2 currently lists 5 recruiting studies that include Pregnenolone, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Pregnenolone trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Pregnenolone an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Pregnenolone or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.