Pregnenolone for anxiety and depression in veterans
Treatments studied
Part of Mental health, Pain clinical trials.
This study tests whether a dietary supplement called pregnenolone can improve day-to-day function in veterans struggling with anxiety and depression. It is a 12-week program that combines the supplement with your usual care, and the goal is to help you feel better and do more of what matters to you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You receive care at the Durham VA Health System.
- You have at least moderate symptoms of anxiety or depression (score of 20 or above on a standard questionnaire).
- If you are a woman, you must use a non-hormonal birth control method or not be able to become pregnant.
- Your mental health medications will need to stay the same during the study.
- You must not be taking benzodiazepines (like Xanax or Valium) or opioid pain medications.
- You must not have post-traumatic stress disorder (PTSD) with a certain severity score.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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