Pregnenolone for anxiety and depression in veterans
Treatments studied
Part of Mental health, Pain clinical trials.
This trial tests whether a dietary supplement called pregnenolone can help veterans with anxiety and depression feel better and function better. It's a new approach that may be added to your current treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a veteran getting care at the Durham VA.
- You have at least moderate symptoms of anxiety and depression (score of 20 or higher on a combined questionnaire).
- If you are a woman of childbearing age, you must use a non-hormonal birth control method (like a copper IUD or condoms).
- You cannot have a current PTSD diagnosis or have high PTSD symptoms.
- You cannot be taking benzodiazepines (like Xanax) or opioid painkillers.
- You cannot be pregnant or breastfeeding.
- Your psychiatric medications must be stable (no changes planned) for the study duration, and no changes in the 4 weeks before starting.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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