Capsaicin-like drug for severe cancer pain
Part of Pain clinical trials.
This Phase 1 trial tests a new drug related to capsaicin (resiniferatoxin) to reduce severe nerve pain from advanced cancer. It is given through a small catheter near the spinal fluid space and is meant for people whose pain medicines and other options have not worked well enough.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have advanced cancer that has not responded to standard treatments (with pathology proof).
- Your pain is cancer-related and very severe—an average “worst pain” score of 6 or more/10 on most days, measured at the chest level or lower.
- You have tried other pain control options, but they were not effective, not appropriate, not tolerated, or you refused them.
- You can safely get MRI scans and a catheter procedure, and you can return for follow-up for 30 days.
- You have recent blood test results that meet clotting and platelet requirements, and you can stop blood thinners/antiplatelet meds for the catheter placement.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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