Registry for people with inherited very high cholesterol
Part of Genetic & congenital, Hormones & metabolism clinical trials.
This trial is a registry that collects information from people with homozygous familial hypercholesterolemia (an inherited condition causing extremely high “bad” cholesterol). It may help researchers better understand the condition and support future studies.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a diagnosis of homozygous familial hypercholesterolemia based on clinical features and/or genetic testing
- Your fasting LDL (“bad” cholesterol) is above 500 mg/dL while your triglycerides are below 200 mg/dL, even while following a cholesterol-lowering diet for at least 8 weeks
- You have supporting evidence such as DNA showing specific LDL receptor or apoB gene changes, or strong family history of very early heart disease, or certain skin/tendon cholesterol deposits
- If your triglycerides stay high or other causes of high cholesterol weren’t ruled out, you may not qualify
- You (or a parent/guardian if you’re under 18) can sign informed consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study is a registry (a list that collects health information) for people with homozygous familial hypercholesterolemia, a genetic cholesterol condition. It helps researchers understand this condition better and connect patients with future research.
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This trial is about helping families with familial hypercholesterolemia (a genetic condition that causes very high cholesterol) get screened. It tests a way to reach close relatives so they can learn their risk and consider next steps.
This registry collects information from people with inherited high cholesterol to better understand the condition and care needs. You may be invited to share blood and medical test results, especially your cholesterol and related health history.
This registry study collects information from people with familial hypercholesterolemia (a genetic condition causing very high cholesterol) to better understand the disease and improve care. By participating, you help researchers learn more about this condition.
This trial focuses on people with familial hypercholesterolemia (FH), an inherited condition that causes very high cholesterol. It aims to better understand and manage severe cholesterol problems that raise heart risk, especially in families.
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