Study for inherited high cholesterol in families
Part of Genetic & congenital, Heart & circulation, Hormones & metabolism clinical trials.
This trial focuses on people with familial hypercholesterolemia (FH), an inherited condition that causes very high cholesterol. It aims to better understand and manage severe cholesterol problems that raise heart risk, especially in families.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You (or close family) have a history of very high cholesterol
- You (or close family) have a history of heart disease at an early or severe level
- You have signs linked to FH, such as cholesterol buildup in tendons or fatty spots in the eye
- You have a family history of FH specifically
- You have severe problems with cholesterol or other blood fats
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study aims to find and help people with very high cholesterol, which can run in families. If you or your child have high cholesterol, this study may help you understand your risk and get the right care.
This registry collects information from people with inherited high cholesterol to better understand the condition and care needs. You may be invited to share blood and medical test results, especially your cholesterol and related health history.
This trial focuses on people referred to a cholesterol (lipid) clinic to help identify inherited high cholesterol. It tests an “interpretive comment” approach to nudge detection—meaning it may help clinicians recognize who is most likely to have familial hypercholesterolemia.
This trial is a global registry that collects health and genetic information from people with familial hypercholesterolemia (FH) and sometimes from their relatives. The goal is to better understand FH and how it presents, which can help improve care for families affected by high cholesterol.
This trial is about helping families with familial hypercholesterolemia (a genetic condition that causes very high cholesterol) get screened. It tests a way to reach close relatives so they can learn their risk and consider next steps.
This study uses a 'cascade testing' approach, where family members of people with familial hypercholesterolemia (FH), a genetic condition causing very high cholesterol, are tested to see if they also have it. The goal is to identify and test at-risk relatives early so they can get treatment to prevent heart problems.
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