Parkinson’s genetics study for adults in affected families

This study builds a genetics “registry” of people diagnosed with Parkinson’s disease who agree to genetic testing. Your information may help researchers understand why Parkinson’s happens and improve future treatments.

This project is for people age 16 and older who have Parkinson’s (or similar symptoms called parkinsonism). It focuses on people with a family history and/or symptoms that started before age 45, to better understand Parkinson’s in families.

This study uses advanced genetic testing (genome and RNA sequencing) to find the genetic causes of Parkinsonism that starts before age 40 or runs in families. If you join, you will provide a blood sample and a small skin biopsy to help researchers understand your condition better.

This study is building a large, detailed group of people—some with Parkinson’s and some at higher risk—to understand early changes over time. It uses brain imaging (DaTscan SPECT), sometimes spinal fluid tests (lumbar puncture), and genetic information to help researchers better measure disease and develop future treatments.

This trial is a research registry that collects health and family information from people with Parkinson’s disease (and sometimes their close relatives). It may help doctors better understand how Parkinson’s runs in families.

This research study follows people with Parkinson's disease, especially those with genetic changes in PRKN or PINK1 genes, to understand how the disease develops over time. Researchers will also study people who carry these genetic changes but don't have Parkinson's symptoms yet, and healthy volunteers, to learn why some people develop the disease and others don't.