Disulfiram and copper after surgery for new glioblastoma
Treatments studied
Part of Cancer clinical trials.
This trial tests whether disulfiram (a medicine) combined with copper can help after surgery in people with newly diagnosed glioblastoma. It aims to improve outcomes by adding treatment before (or instead of) standard chemoradiation starts.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have newly diagnosed glioblastoma (WHO grade 4) and it is a single (one area) tumor above the brain stem
- You had a surgery that removed the tumor as completely as possible, and a brain MRI within 72 hours shows only minimal leftover tumor
- You can start disulfiram on day 5 after surgery
- You are age 18 or older and able to do daily activities fairly well (Karnofsky score 70 or higher)
- Your blood counts, liver, and kidney tests are within allowed ranges, and blood-clotting tests are acceptable
- You have not had chemotherapy or radiation for the brain tumor yet, and you can have MRI scans
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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