Diet study to lower TMAO levels using gut microbes
Part of Digestive system, Heart & circulation clinical trials.
This trial looks at whether a structured 12-week diet can lower a blood chemical called TMAO, which is linked to heart and kidney risk for some people. It may help you see if diet changes can shift gut microbes and reduce TMAO-related signals.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be age 18 or older
- Have higher TMAO levels (over 5 µM) and/or reduced kidney function (eGFR under 60)
- Be able to keep the same aspirin plan during the study, or pause aspirin products for 1 week before starting
- Be willing and able to follow a 12-week diet change and sign consent
- Not be pregnant
- Not have a major uncontrolled long-term illness (like unstable heart failure or serious lung/bleeding blood problems)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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