Metreleptin safety and effectiveness registry
Treatments studied
Part of Genetic & congenital, Hormones & metabolism, Skin clinical trials.
This registry follows people who are already taking metreleptin (a medicine for certain rare conditions) to better understand its long-term safety and how well it works in everyday use. It may help you and other patients by building real-world evidence about this treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You take metreleptin from regular (commercial) supply now or started it before joining
- You can sign a written consent form to join the registry
- You are coming from a previous metreleptin study and you are continuing or restarting metreleptin through regular supply
- You are not taking an investigational (study-only) medicine as part of another clinical trial
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests an open-label study of metreleptin in people with partial lipodystrophy, a condition where fat is lost from some areas of the body. The goal is to see if the drug can help manage related health problems.
This Phase 2 study tests pegvisomant, a medicine that blocks growth hormone, to see if it can improve severe insulin resistance in people with a specific genetic cause or a rare fat distribution condition. If you fit the rare diagnosis, the study may help clarify whether growth-hormone blocking can improve blood sugar and related health markers.
This study tests the long-term safety of metreleptin for people with partial lipodystrophy. It is for those who already completed a related study and want to continue treatment.
This trial tests new medicines for adults with fatty liver disease (MASLD) that has already caused some liver scarring. It aims to see if these drugs can help prevent the liver disease from getting worse.
This study looks at how pregnancy goes and what birth outcomes happen in women with lipodystrophy, comparing those who used metreleptin during pregnancy versus those who did not. It also collects information and blood samples from the children so researchers can better understand the effects of metreleptin during pregnancy.
This study tests a drug called metreleptin (a version of a hormone that helps regulate appetite and weight) in people hospitalized for anorexia nervosa. It may help with weight restoration and mood.
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