Penile transplant trial using immune-suppressing medicines
Treatments studied
Part of Genetic & congenital, Injuries & trauma clinical trials.
This study tests whether a donated penis can be successfully transplanted using medicines that calm the immune system to prevent rejection. It also looks at safety and recovery of function in men with severe penile loss from injury, cancer surgery, or birth conditions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be a male 18 to 69 years old (penile cancer survivor or other qualifying cause).
- Have lost at least 75% of the penis from injury, cancer surgery, or a congenital condition (like micropenis).
- Have finished a clinic visit with the study surgeons to talk through reconstructive options and sign the consent forms.
- No HIV infection, and no active or recent serious infections like hepatitis B/C or tuberculosis.
- Agree to extra medical steps: skin sampling (biopsy) and bone-marrow infusion as part of treatment.
- Be able to follow the immune-suppressing medicine plan and have no major substance-use problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests replacing a missing or non-working lower arm/hand with a donated upper limb (transplant). It also uses a special immune treatment plan and bone marrow infusion to help the body accept the new limb, aiming to improve hand function and quality of life.
This study follows people who received a transplanted arm (or both arms) to learn from their ongoing care. You may be asked for small tissue samples (biopsies) and to continue an immunotherapy plan to help protect the transplant.
This trial tests adding your own fat tissue beneath a skin graft during penis reconstruction surgery. The fat may help improve the result of the graft.
This trial studies whether a transplanted hand can work safely and successfully for adults who are missing all or part of a hand and forearm. You may be considered if you’ve tried a prosthetic (artificial hand) or it hasn’t worked well for you.
This trial studies a special surgery to replace part of the skull, face, and jaw using donor tissue. It also tests medicines to help your body accept the transplant, aiming to restore function and appearance after serious injury.
This is an experimental study to see if a penis transplant (from a donor) can work for men who lost their penis from injury or were born with an underdeveloped one. You will need to be healthy enough for major surgery and take anti-rejection drugs for life.
Hear when a new Amputation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.