Low-dose naltrexone for complex regional pain syndrome
Part of Brain & nervous system clinical trials.
This trial tests whether low-dose naltrexone can reduce symptoms of complex regional pain syndrome (CRPS), a long-lasting pain condition in an arm or leg. It may help by targeting pain signaling, but you must meet specific CRPS diagnosis and medication rules to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have CRPS affecting an arm and/or a leg
- Your CRPS symptoms have been present for at least 1 year
- Your CRPS treatment plan has stayed the same for at least 1 month
- Your CRPS diagnosis matches the Budapest criteria (your clinician confirms this)
- You cannot be allergic to naltrexone or naloxone
- You must not currently use prescription opioid pain medicines (or use illegal opioids)
- You cannot be pregnant, and you cannot plan a pregnancy during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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