Low-dose naltrexone for nerve pain from diabetes
Treatments studied
Part of Brain & nervous system, Hormones & metabolism clinical trials.
This Phase 2 trial studies whether a low dose of naltrexone can reduce painful nerve pain caused by diabetes. It may help people whose diabetic nerve pain did not improve with at least one standard treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have painful diabetic nerve pain (diabetic neuropathy) for more than 6 months
- At least one prior treatment for this pain (like gabapentin or duloxetine) did not work
- Your lower-leg nerve pain is believed to be from diabetes, not another cause
- You’re over 18 and able to understand and sign consent
- You have been on stable non-opioid pain medicines for at least 1 month
- You mainly speak English
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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