Clin2
NCT02568878Possibly a fitRecruiting

Creatine to help depression and anxiety in meth users

DepressionAnxietyMethamphetamine Dependence

Part of Mental health clinical trials.

This trial studies whether creatine can reduce depression and anxiety symptoms in people who currently use methamphetamine and also have depression and anxiety. It may help by improving mood and anxiety scores over the course of the study.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
29 people
Ages
18 years to 59 years
Study type
Interventional

Who can take part

  • You currently have a methamphetamine dependence or abuse diagnosis, and meth is your main drug
  • You currently have major depression (either from yourself or related to substance use)
  • You currently have an anxiety disorder (either from yourself or related to substance use)
  • Your depression and anxiety symptom scores are high enough for the trial (depression score 16+ and anxiety score 18+)
  • If you take antidepressant or anxiety medicines, your dose must have been stable for at least 4 weeks before starting creatine

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06424184Recruiting
Fast brain stimulation for addiction and depression

This study tests a quick, non-invasive brain stimulation method (rTMS) to help people who use stimulants like cocaine or methamphetamine and also feel depressed. The goal is to see if it can reduce cravings and improve mood.

Dallas, Texas
NCT06876129Recruiting· Phase 1
Adding D-serine to TMS for depression

This trial tests whether adding a medication called D-serine to a brain stimulation treatment (TMS) helps improve depression. It’s for adults with major depression who are already getting TMS therapy.

Belmont, Massachusetts
NCT05895747Recruiting· Phase 2
5-HTP and creatine for adults with depression symptoms

This Phase 2 study tests whether adding 5-HTP and creatine can reduce depression symptoms in adults with major depressive disorder. It may help if your current depression treatment hasn’t been fully effective and you meet the safety and medical criteria.

Salt Lake City, Utah
NCT06323837Recruiting· Phase 2
Testing mirtazapine for methamphetamine use in people on opioid treatment

This trial tests whether the antidepressant mirtazapine can help reduce methamphetamine use in people who are already receiving medication for opioid use disorder. It aims to see if adding this medication improves outcomes for those struggling with both conditions.

Spokane, Washington
NCT07633080Recruiting
Magnesium supplement added to antidepressants for depression

This study tests whether adding magnesium bisglycinate (a mineral supplement) to your current antidepressant medication can help improve depression symptoms. Researchers want to see if this combination works better than antidepressant alone.

Bhubaneswar, Odisha
NCT07774702Not yet recruiting· Phase 2
Psilocybin for methamphetamine use disorder

This trial tests whether a psychedelic drug called psilocybin can help people cut down or stop using methamphetamine. You'll take the drug in a supervised setting and get support to aim for full abstinence.

Birmingham, Alabama

Hear when a new Depression trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.