Clin2
NCT02610413Possibly a fitRecruiting

DNA testing to explain who gets severe blood pressure with bevacizumab

Breast Carcinoma

Part of Cancer, Skin clinical trials.

This study uses whole exome DNA testing to look for inherited genetic differences that may explain why some people develop very high blood pressure from bevacizumab during breast cancer treatment. It compares people who did vs. did not develop severe bevacizumab-related hypertension.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
354 people
Ages
Any age
Study type
Observational

Who can take part

  • You are a European American patient with available DNA for testing
  • You must have been treated with bevacizumab for breast cancer
  • You developed severe (grade 3–4) hypertension caused by bevacizumab during treatment
  • You were able to provide DNA samples and your sample can be used as a case or control

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT02610426Recruiting
Genetic testing to study who develops heart failure during breast cancer therapy

This study uses DNA genetic testing to find DNA changes that might explain why some people develop heart failure (CHF) after breast cancer treatment with certain medicines. It may help researchers understand risk and improve care for future patients.

Boston, Massachusetts
NCT02610439Recruiting
Genetic testing to find causes of paclitaxel nerve damage

This study uses genetic tests on blood DNA to look for differences that may explain why some people develop nerve pain (peripheral neuropathy) from paclitaxel used for breast cancer. It compares people who got significant neuropathy during treatment with people who did not get neuropathy after completing paclitaxel.

Boston, Massachusetts
NCT06336928Recruiting
Blood test validation for breast cancer diagnosis

This study is testing a new blood test (liquid biopsy) to see if it can accurately detect breast cancer or track remission. If you are a woman getting a mammogram, have an abnormal finding, were recently diagnosed, or are in remission after treatment, you may be able to join and help validate this test.

Los Angeles, California
NCT07445347Enrolling by invitation
Bevacizumab for severe HHT liver issues with high heart output

This study looks at how well the drug Bevacizumab works and how safe it is for people with HHT who have severe liver problems that cause their heart to pump too much blood. It aims to help doctors understand if this treatment can help manage these serious symptoms.

Poitiers
NCT06726642Recruiting
Blood test study for people with inherited cancer risk

This study looks for DNA fragments in blood of people with certain inherited cancer syndromes. It may help find cancer earlier or guide better monitoring. You would give blood samples every 4 months (if in the experimental group).

Vancouver, British Columbia
NCT07734857Not yet recruiting
Blood markers and liver cancer treatment response

This study looks at whether certain blood markers can predict how well the combination of atezolizumab and bevacizumab works for people with advanced liver cancer. It aims to find out if these markers can help guide treatment decisions.

Hear when a new Breast Carcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.