Cord blood stem cell treatment for newborn brain injury
Part of Blood & lymphatic, Brain & nervous system, Genetic & congenital clinical trials.
This early-phase study tests whether using a baby’s own cord blood stem cells is safe and feasible for newborns with brain injury from lack of oxygen around birth. It may help researchers find new ways to treat hypoxic-ischemic encephalopathy (brain injury due to oxygen deprivation) in addition to standard care like cooling.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby was born at or after 36 weeks of pregnancy (term).
- At birth (or within 60 minutes), the baby had concerning blood gas results showing oxygen/acid stress, OR met specific birth emergency signs plus low Apgar score or ongoing breathing support at 5 minutes.
- Your baby showed signs of brain injury within 12 hours after birth (an exam score of at least 2).
- Your baby is receiving therapeutic hypothermia (treatment using cooling to protect the brain).
- The baby’s mother does not have certain infections (HIV, HTLV-1/2, hepatitis B or C) and has a negative syphilis test.
- No major birth defects, no known chromosome problem, no very low birth weight (under 1800g), and doctors plan further intensive care if needed; parents must give written consent.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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