Cord blood infusion for children with brain injuries
Part of Brain & nervous system, Heart & circulation, Injuries & trauma clinical trials.
This trial gives children with brain injuries an infusion of stem cells from their own or a sibling's umbilical cord blood, or from a matched donor. The goal is to see if these cells can help repair brain damage and improve function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age: 0 to 26 years for autologous (own) cord blood; 6 months to 26 years for sibling or unrelated donor cord blood (Duke only)
- Diagnosis: Cerebral palsy, hypoxic-ischemic encephalopathy (lack of oxygen to the brain), stroke, hydrocephalus, apraxia, or other brain injury
- Have an available cord blood unit that meets quality standards (e.g., cell count, viability, and for unrelated donor, HLA match)
- No serious blood count or chemistry abnormalities, no uncontrolled seizures, no active infections, no immune deficiency or history of chemotherapy
- Parent or legal guardian must provide informed consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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