Cancer vaccine made from your own cells after bowel cancer surgery
Part of Cancer, Digestive system clinical trials.
This trial tests whether a personalized vaccine—made from your own immune cells mixed with your own tumor material—can help prevent colorectal cancer from coming back after curative surgery. It may help your immune system recognize and fight any remaining cancer cells.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have stage IV colorectal cancer that was fully removed with surgery intended to cure.
- Your removed tissue must be collected and successfully processed at their lab to meet strict quality rules.
- Recent scans (CT or MRI) within 60 days show no signs of cancer; if cancer was in other places before, those areas must be included in the scan.
- You must have recovered well from surgery and prior treatment side effects (no significant ongoing problems from surgery).
- You must be age 18 or older and well enough to do daily activities (performance status 0–1).
- Blood tests and organ tests must be within acceptable ranges; heart function must be checked if you are 70 or older.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a personalized vaccine made from your own tumor material, aiming to lower the chance cancer returns after surgery. It is for people whose rare cancers have been removed completely and who have no standard treatment available after surgery.
This trial tests a sequence of treatments for people with a specific type of advanced colorectal cancer (called pMMR or MSS) that has not responded to earlier therapies. Patients first receive an immunotherapy combination (pembrolizumab plus a personalized dendritic cell vaccine) followed by a chemotherapy pill (trifluridine/tipiracil) plus bevacizumab. The goal is to see if this sequence can help control the cancer.
This early-phase trial tests a whole-cell cancer vaccine for people with certain metastatic cancers. It aims to help your immune system recognize and fight the cancer, especially when prior chemotherapy hasn’t worked.
This trial tests a treatment made from your own immune cells (called TILs) that are taken from your tumor, grown in a lab, and given back to you along with immunotherapy. It is for people with advanced colon or rectum cancer who have run out of standard options.
This trial tests a personalized vaccine (ODI-2001) that is made from your own tumor. It is given during a break from chemotherapy to see if it is safe and can help keep the cancer from growing.
This trial tests a personalized vaccine made from your tumor's unique features, combined with a standard second-line treatment, for colorectal cancer that has worsened after the first treatment. The goal is to see if this combination can help control the cancer better than standard therapy alone.
Hear when a new Stage IV Colorectal Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.