Clin2
NCT02971358Possibly a fitRecruiting

Surgery for very high-risk or limited-spread prostate cancer

Locally Advanced and Metastatic Prostate Cancer

Part of Cancer, Kidney & urinary clinical trials.

This trial looks at how safe and how well early prostate surgery works for men with newly diagnosed very high-risk prostate cancer or a limited number of metastases (cancer spread). It may help some people live longer and control the cancer, but eligibility is very specific.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
200 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have prostate cancer confirmed as adenocarcinoma
  • Your cancer is either very high risk (based on PSA, Gleason score, or tumor stage) and/or has limited spread (oligometastatic)
  • You have 5 or fewer bone metastases
  • You are 18–75 years old and can give informed consent
  • Your scan/exam shows no spread to internal organs (visceral metastasis) and no cancer invading the rectum or pelvic wall
  • You are healthy enough for surgery (ECOG 0–1, meaning fully active or limited but up and about)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04093375Not yet recruiting
Surgery versus radiation for locally advanced prostate cancer

This trial compares radical prostate surgery versus radical radiation for men with locally advanced, non-spread prostate cancer. It aims to see which treatment works better for cancer control while considering safety and recovery.

NCT06758882Recruiting· Phase 2
Surgery with or without apalutamide for high-risk prostate cancer that has spread a little

This trial tests whether adding the drug apalutamide before and after surgery helps men with high-risk prostate cancer that has spread to a few spots (seen on a special PET scan). You would also receive standard hormone therapy.

Torino, To
NCT07268794Not yet recruiting· Phase 2
Surgery after hormone therapy for advanced prostate cancer

This trial is testing if removing the prostate with surgery, after starting hormone therapy, helps men with advanced prostate cancer that has spread to many parts of the body. It aims to see if this approach improves outcomes compared to hormone therapy alone.

Shanghai
NCT02102477Recruiting
Surgery or radiation for prostate cancer in the pelvis

This trial compares surgery versus radiation for men with locally advanced prostate cancer that has not spread to distant sites. It aims to see which treatment works better and is easier to manage for people like you.

Aalborg
NCT06306612Recruiting
Surgery plus hormone therapy for advanced prostate cancer

This trial tests whether removing the prostate (surgery) plus standard hormone therapy and chemotherapy can help men whose prostate cancer has spread to many places in the body. It is for men who have not yet had treatment for their cancer.

Shanghai, Shanghai Municipality
NCT06992232Recruiting· Phase 2
Radiation or surgery plus hormone therapy for prostate cancer that has spread

This trial tests whether giving intense hormone therapy along with either radiation or surgery can help men with prostate cancer that has spread to a limited number of spots (10 or fewer) but not to organs like the liver or lungs. The goal is to treat both the main tumor and the visible metastatic spots more aggressively.

Nanjing, Jiangsu

Hear when a new Locally Advanced and Metastatic Prostate Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.