Tested immune therapy before surgery for early colon cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This Phase 2 trial tests immune “checkpoint” medicines (and combinations) given before colon surgery to see if they can better control early colon cancer. It is aimed at people with non-metastatic colon cancer and certain tumor markers.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older and can sign consent
- Your colon (or rectosigmoid) cancer has not spread to distant organs (no metastases on CT scan and exam)
- You have colon cancer that is adenocarcinoma, and your tumor type fits the study’s groups (dMMR or MSS with specific limits)
- You must be able to get study-specific biopsies from a colonoscopy after enrollment
- You have good day-to-day functioning (WHO performance status 0 or 1)
- You have not had immune drugs that target CTLA-4, PD-1, or PD-L1 before
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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