Letrozole for recurrent high-grade brain tumors
Treatments studied
Part of Brain & nervous system, Cancer clinical trials.
This early-phase study tests letrozole, a hormone-blocking medicine, in adults with recurrent high-grade gliomas. The goal is to see if it can help control the tumor and is safe enough to study further.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have a confirmed recurrent high-grade brain glioma, and doctors plan a biopsy or surgery
- You can do daily activities fairly well (ECOG 0–2 or similar), and your labs are strong enough for treatment
- Recent bloodwork, liver tests, and kidney tests must be within required limits
- You must be able to get a brain MRI (with or without contrast) before treatment and sign consent
- If you are able to become pregnant, you need a recent negative pregnancy test; you must not be pregnant or breastfeeding
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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