FETO surgery to help a baby’s lungs in left diaphragmatic hernia
Part of Genetic & congenital, Lungs & breathing clinical trials.
This trial studies a specialized pregnancy procedure (FETO) done to help babies with a defect in the diaphragm called congenital diaphragmatic hernia (CDH) grow better lungs before birth. It may help by improving lung development, based on how severe the baby’s lung underdevelopment looks on ultrasound, and it requires close follow-up at the study hospital.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are pregnant with only one baby (not twins or more).
- Your baby’s chromosomes are expected to be normal based on test results.
- The CDH must be isolated and on the baby’s left side, with the liver up.
- Ultrasound must show severe lung underdevelopment in specific ranges (measured as an LHR percentage at certain weeks).
- You must be able to travel to the study hospital for frequent follow-up (within about 30 minutes drive) and have a support person available to stay during your pregnancy at their center.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a special pregnancy procedure called FETO to help babies born with severe congenital diaphragm hernia (CDH) breathe better after birth. It may help by improving lung growth, but it requires close follow-up at a Chicago fetal center.
This trial tests if a special surgery (FETO) done while the baby is still in the womb can improve survival for babies with a severe form of congenital diaphragmatic hernia (CDH). The surgery places a small balloon in the baby's windpipe to help the lungs grow. We are looking for pregnant women whose baby has a left-sided CDH with a lung-to-head ratio (LHR) less than 30%, or a right-sided CDH with LHR less than 45%, and whose liver is herniated into the chest.
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