Prevent return of esophagus pre-cancer after endoscopy
Part of Cancer, Digestive system clinical trials.
This trial looks at a prevention treatment to stop esophagus abnormal growth (pre-cancer or very early cancer) from coming back after successful endoscopic submucosal dissection. It focuses on people whose esophagus lining shows a “speckled” pattern on a special iodine test, which may mean higher risk of recurrence.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re an adult (18 or older) with early esophagus squamous disease such as high-grade dysplasia, carcinoma in situ, or T1N0M0 squamous cell cancer
- You were treated successfully with endoscopic submucosal dissection (ESD) to remove the abnormal area
- Your iodine (Lugol) staining test showed a “speckled” pattern with more than 10 small unstained spots
- Your previous endoscopic treatment had no major problems like perforation (a tear) or problematic narrowing (stricture)
- You have not had chemotherapy or radiation for the esophagus, and you have not had surgery to remove the esophagus (esophagectomy)
- You have enough health to likely live at least 2 years, with good enough function and not severe liver disease
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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