CAPTEM pills after brain radiation for newly diagnosed glioblastoma
Treatments studied
Part of Brain & nervous system, Cancer clinical trials.
This trial studies whether taking two chemotherapy pills (capecitabine and temozolomide) after the initial 6-week radiation-and-chemo phase can help people with newly diagnosed glioblastoma. It aims to test safety and early effectiveness right before the usual maintenance temozolomide phase.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You can sign consent and clearly understand the study.
- Your glioblastoma diagnosis was confirmed by pathology (biopsy/surgery results).
- You finished the first 6 weeks of standard radiation plus chemo, and you have not started the usual next-phase temozolomide maintenance yet.
- You can swallow pills and your body can tolerate oral chemotherapy based on labs and exam.
- Your blood counts, kidney, and liver tests are strong enough before starting treatment.
- You are age 18–74, expected to live more than 3 months, and your function level is good (KPS 70 or higher).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study is testing whether a short course of chemotherapy (temozolomide) given before radiation can improve outcomes for people with newly diagnosed high-grade gliomas. It is designed for patients who are stable enough to delay starting radiation by a few weeks.
This early-phase study tests whether liposomal curcumin, added to standard radiation plus temozolomide, can improve treatment outcomes in newly diagnosed high-grade gliomas. It focuses on safety and how well the treatment can be given with the usual therapy plan.
This trial tests a combination of two drugs—vebreltinib and temozolomide—for people with a type of brain cancer called glioblastoma. It is for those who have already had surgery to remove as much of the tumor as possible.
This trial tests whether a type of chemotherapy called anthracycline can help young patients with glioblastoma when given after radiation therapy. It aims to see if this treatment improves outcomes for patients aged 3 to 30.
This trial tests a combination of two drugs, bortezomib and temozolomide, for people whose brain tumor (glioblastoma) has returned after initial treatment. It's designed for tumors that don't respond well to standard treatments, and the goal is to see if this combination can help control the cancer.
This trial tests putting radiation directly into the brain right after surgery for glioblastoma, instead of waiting for standard radiation later. It aims to see if this approach works better and is safe for you.
Hear when a new Glioblastoma Multiforme (GBM) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.