Single-dose SBRT for early prostate cancer
Part of Cancer, Kidney & urinary clinical trials.
This trial tests a very short, one-time form of radiation (SBRT) to treat prostate cancer. It aims to see whether treating the prostate in one shot is safe and effective for carefully selected patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must sign informed consent before any study steps begin.
- Your prostate cancer must be confirmed by biopsy as typical prostate adenocarcinoma (not a small-cell type).
- Your cancer stage must be early: T1c to T2c, with no spread to lymph nodes or other body sites on scans (M0, N0).
- Your biopsy Gleason score must be 3+3 or 3+4 (not higher).
- Your PSA must be 15 ng/mL or less, and you should be well enough for study treatment (performance status 0–1) with urinary symptom score 10 or less.
- Your prostate size on MRI must be 70 cc or less, and you must be able to have small tracking beacons (Calypso) placed so the team can target radiation accurately.
- You must not have had prior pelvic radiation or prostate cancer surgery, and no prostate procedure like TURP within the last 12 weeks.
- You must avoid fathering a child during treatment and for 6 months after (birth-control guidance will be needed).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a newer, more precise radiation treatment that gives a higher dose to the main tumor while keeping radiation to the rest of the prostate the same. It is for men with intermediate- or high-risk prostate cancer who haven't had prior prostate radiation or removal.
This trial tests whether a single, high dose of radiation can treat low- to intermediate-risk prostate cancer. It may be a shorter and more convenient option for eligible patients.
This observational study looks at how well men with localized prostate cancer do when treated with an unusually short radiation approach. It may help doctors understand which patients benefit most by tracking outcomes and imaging over time.
This trial studies a more sped-up radiation schedule for men with certain local prostate cancers, given together with hormone therapy. It aims to keep cancer control while possibly reducing treatment time and making care easier.
This early-phase study tests a prostate radiation approach given in two treatments, planned using MRI. It’s designed for men with lower-to-intermediate risk prostate cancer and aims to see if this method is safe and works well.
This trial tests a radiation approach that delivers treatment in a small number of larger “fractions” (short-course SBRT) for prostate cancer. It may help by targeting the prostate while shortening the overall number of visits.
Hear when a new Prostate cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.