Registry for certain inherited spinocerebellar ataxias

This is a natural history study that follows people with inherited forms of “ataxia” (problems with balance and coordination) over time. It may help researchers better understand how these conditions progress in daily life and can inform future treatments.

This trial looks for eye problems in people with certain genetic forms of spinocerebellar ataxia (SCA1, SCA2, SCA3, or SCA27B). You have to be between 18 and 80 years old and have a specific genetic mutation. You can join if you already have symptoms or if you are at risk but do not have symptoms yet.

This study follows people with certain types of spinocerebellar ataxia (a group of conditions that cause progressive movement problems) to understand how the disease changes over time and how genes might influence it. It may help researchers learn more about these conditions and support future treatments.

This registry collects information from people with hereditary spastic paraplegia or spastic ataxia to help plan future treatments. It aims to better understand the condition and connect patients with potential therapies.

This study follows people with spinocerebellar ataxia type 27B (a movement disorder) and their family members to understand how the condition changes over time. It also includes healthy volunteers for comparison.

This study looks for biological “markers” (measurable signs in the body) in people with inherited movement disorders, and in some related family members or healthy volunteers. It may help researchers better understand these conditions, especially for future diagnosis and care.