Testing a sedative’s effect on anesthesia dose needs in toddlers
Treatments studied
This study looks at whether dexmedetomidine changes the minimum amount of sevoflurane (an inhaled anesthesia medicine) needed during surgery in young children. It may help doctors choose safer, more accurate anesthesia dosing for kids undergoing surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 1 month and 3 years old
- Be having surgery that requires sevoflurane anesthesia
- You must not have lung or chest conditions that cause flare-ups within the last 2 weeks
- You must not have a history of difficult intubation or ventilation (placing a breathing tube or using a ventilator)
- You must not have certain heart rhythm problems or heart birth defects
- You must not have certain nerve/brain conditions (like seizures or cerebral palsy) or a history of malignant hyperthermia
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a combination of two medicines (dexmedetomidine and esketamine) given as a nasal spray to help children relax before surgery. The goal is to find the best dose that works well with the least side effects.
This study compares two medicines to see which works better at preventing agitation and restlessness when children wake up from surgery with a common anesthetic. The goal is to help children recover more calmly and comfortably.
This study tests a skin patch that helps children relax before surgery. The patch contains a medicine that is absorbed through the skin to reduce anxiety, so the child may need less anesthesia.
This trial tests adding a sedative medicine called dexmedetomidine to standard anesthesia for children aged 3 to 12 who are having a procedure to close a hole in their heart (atrial septal defect). The goal is to see if it helps them recover more smoothly.
This study compares two sedative medicines given as a nasal spray to help children relax and reduce separation anxiety before surgery. It aims to find which medicine works better for children aged 2 to 6.
This trial looks at whether a monitoring method for how deeply a child is sedated matches how the child’s reflexes react during intravenous anesthesia. It may help anesthesiologists keep children safer and more comfortable during direct laryngoscopy procedures using medications like dexmedetomidine and remifentanil.
Hear when a new Pediatric Anesthesia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.