Tempol to reduce mouth and other side effects from radiation and cisplatin
Part of Digestive system, Ear, nose & throat, Injuries & trauma, Mouth & dental clinical trials.
This Phase 2 trial tests tempol to lessen harmful side effects caused by head-and-neck radiation and the chemotherapy drug cisplatin. If you qualify, you may receive tempol during treatment to help protect normal tissues and reduce toxicity.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be at least 18 years old and have diagnosed squamous cell cancer of the head and neck
- Plan to receive radiation (radiotherapy or proton therapy) with the goal of cure
- Be receiving cisplatin chemotherapy as part of your cancer treatment
- If you can get pregnant: use reliable birth control; if you are a man who could father a child: use contraception (including condoms with spermicide) and avoid sperm donation for 90 days
- Be able to do daily activities at a fairly good level (ECOG score of 0–2) and expect to live at least 6 months
- Your bloodwork and organs (kidneys, liver, blood counts) must be strong enough for study treatment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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