Clin2
NCT03701581Possibly a fitRecruiting

4-aminopyridine to help erections after prostate nerve surgery

Nerve InjuryProstate Cancer

Treatments studied

Part of Cancer, Kidney & urinary, Mental health clinical trials.

This trial tests whether a medicine called 4-aminopyridine (4AP) can help recover or protect erectile function after “nerve-sparing” prostate surgery. It’s for men with early-stage, non-spread prostate cancer who are scheduled for robotic prostate surgery and have good baseline erections.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
70 people
Ages
45 years to 75 years
Study type
Interventional

Who can take part

  • You are a man age 45–75 with early-stage prostate cancer that has not spread (organ-confined, stages cT1c–T2c).
  • Your PSA blood test is under 15 ng/ml within the last 12 months, and the cancer was confirmed by biopsy.
  • You have a good starting erectile function score (IIEF-5 of 17 or higher).
  • You are scheduled for robotic “nerve-sparing” prostatectomy and do not expect to need added cancer treatment right after surgery.
  • You can commit to not using erectile dysfunction treatments until 3 months after surgery and are able to consent.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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