Testing medicines to prevent heart events in opioid constipation
Part of Mental health clinical trials.
This study looks at how well naldemedine (and certain other constipation medicines) lower the risk of major heart problems in people who take opioids for constipation. It compares medicine use patterns in people with opioid-induced constipation to see who has fewer serious heart events.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You have been getting prescriptions for opioids at least two times in the last 6 months, totaling at least 31 days of supply.
- You have health insurance coverage with both medical and pharmacy benefits continuously for at least 6 months before starting the study medicines.
- You have not used naldemedine, lubiprostone, or naloxegol before the start date.
- You did not have a heart attack or stroke in the 6 months before the start date.
- You have not had cancer treatment or cancer-related pain in the last 6 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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